Iranian Journal of Medical Microbiology

✅ This study showed that the prevalence of ESBL-positive and MDR bacteria is high in Kermanshah medical centers, and it provides significant information to health policymakers to implement appropriate strategies to reduce the prevalence of resistant bacteria.

✅ In general, the vaccine that was able to have a favorable interaction with some components of the immune system (HLA) in the docking process, which indicates the optimal identification of this structure by the humoral and cellular immune system, of course, more reliable proof of it requires clinical phase processes.

✅ This study established a correlation between T3SS proteins, particularly exoS and exoU genes and antimicrobial resistance in P. aeruginosa isolates from burn infection.

✅ The findings showed that the immune complex (Icx) antigen induced a strong and persistent immunogenic response in terms of antibody titer compared to a conventional live vaccine. Icx provoked better protective immunity and protected chickens against the IBD virus challenge and may be considered a substitute for the IBDV vaccine.

✅ NO (Nitric Oxide) plays a protective role in DF, while in DHF patients, the absence of rising NO levels may be one of the contributory factors leading to the progression of the disease and increased morbidity. NO levels can guide the physician about the evolution of a case of Dengue.

✅ Our study showed that even though changes in miR-222 expression levels in the group of patients with chronic hepatitis B compared to the healthy group, it could not be utilized as a precise diagnostic biomarker, and more studies, on a broader scale, are needed to determine the role of this microRNA in patients with CHB.

✅ The results of this study indicated no association between CMV, BKV, and JCV with ovarian cancer. Therefore, major studies are recommended to confirm these findings.

✅ The existence of different resistant mechanisms in P. aeruginosa can cause cross antibiotic resistance, lead to the appearance of resistant strains, and make the treatment difficult. Biofilm production is directly related to antibiotic resistance. Efflux pumps are actively expressed in carbapenem-resistant strains.

✅ The isolates were highly resistant to ceftazidime, ceftriaxone, piperacillin-tazobactam, cotrimoxazole, imipenem, and levofloxacin; in addition, the frequency of per, veb, tem, and genes was lower in the current study than those reported in other regions.

✅ From this study authors can conclude that carbapenemase-producing Enterobacteriaceae is increasing in Iran and the use of phenotypic methods for detection of CPEs showed good sensitivity. Before prescribing antibiotics to patients, this test should be performed.

✅ The high-level antibiotic resistance to quinolones & fluoroquinolones and heterogeneity of virulence genes among clinical UPEC isolates need strong attention.

✅ The brewed saffron combined with blue light induces a sub-lethal phototoxic reaction in bacteria. Accordingly, it can be suggested as a natural source for new photosensitizers.

✅ Although C. burnetii was not detected in any of the blood samples in this study. However, C. burnetii has a broad and varied host spectrum in the Epizootic and Enzootic foci.

✅ This study also illustrated a low prevalence of Toxoplasma infection in postpartum mothers and no congenital transmission of the disease in diverse health centers of the province. However, there was no statistically significant relationship between risk factors and the prevalence of Toxoplasma.

✅ Monkeypox is a rare zoonotic infectious disease caused by the Monkeypox viruses, a type of Orthopoxvirus of the family Poxviridae, which is endemic to Africa. Due to the importance of the Monkeypox, the present article aimed to introduce this disease as a zoonotic infectious disease that has recently, been reported in several countries.

✅ The sensitivity of all E. coli isolates towards meropenem, calls for attention that the overuse/misuse of this antibiotic will caused the selection pressure and increased the rate of resistance.