Iranian Journal of Medical Microbiology

✅ The result of our work indicates that SAA might potentially be used for the early diagnosis of COVID disease, but more studies are needed.

✅ The current review describes the presence of MRSA, VRSA and VRE in different food samples of animal and plant origin in Iran. Databases including PubMed, ScienceDirect, Scopus, SID, and Google Scholar were searched and a total of 65 articles were retrieved (published between 2006 and September 2020) reporting antibiotic-resistant S. aureus and Enterococcus in food in Iran.

✅ Among the most important conclusions that can be inferred from the trend of word change used in the COVID-19 literature is that the most significant words in international literature differ significantly from those in national literature, as international research focuses on COVID-19 and the infections caused by it. In contrast, national research focuses on COVID-19 and patients. Another significant result is the annual word-changing national and international literature.

✅ Our results showed that HPV 16 and 18 were the most prevalent genotypes among different grades of lesions. The presence of low-risk HPV types, including genotypes 6 and 53, might need more attention in HPV screening and prevention programs.

✅ In this experiment, most of the isolates were identified as E. coli and were resistant to antibiotics. To control the spread of E. coli infectious disease and arbitrary use of antibiotics, it is recommended to conduct some educational programs and social activities with the aim of increasing health awareness.

✅ Inhibition of proliferation and growth of gastric cancer cells by this recombinant protein has been shown to be effective. The anti-apoptotic characteristics of the fusion protein make it useful for both therapeutic and preventative purposes when treating cancer cells.

✅ Accordingly, the extract of A. visnaga can decrease the expression of the Exotoxin A and S genes of P. aeruginosa and consequently it may decrease the pathogenicity of bacteria. These phenomena (exoA and exoS expression inhibition) may involve reducing the antibiotic resistance of P. aeruginosa.

✅ Our study showed the existence of some Omicron-related mutations before the emergence of this variant in Khuzestan Province, Iran. In addition, it Strengthened the possibility of unconfirmed variants, such as Epsilon entering Iran. It also provided a reference for studies that need to be aware of the circulating variants in Iran.

✅ The dropping of the hematological markers in COVID-19 is linked with a noticeably increased mortality rate, while high neutrophil and BS levels are related to aggravation of the disease. Monitoring the hematological markers can contribute significantly to selecting the proper treatment and hamper of disease worsening.

✅ We support the evidence about the significant association between occult HCV infection and impaired immunological response in patients who achieved sustained viral response (SVR) following direct-acting antivirals (DAA) regimens.

✅ The studied combinations of antibiotics showed synergistic effects against the tested Gram-negative bacteria which can help in the control and treatment of serious wound infections.

✅ Both CEO and CN showed promising antimicrobial effects to be used in combating foodborne pathogens.

✅ The results of this study showed that Tocilizumab, despite the lack of an apparent effect on the outcome of the COVID-19 disease (recovery or death), reduced length of hospitalization and the necessity for mechanical ventilation and can be used as an alternative therapy with other treatments.

✅ PCR testing revealed that 105 (47.72%) of 220 S. aureus isolates were positive for the mecA gene. The results of the Cefoxitin disc diffusion method showed that it has similar sensitivity and specificity to PCR method. The sensitivity and specificity of CHROMagar™ MRSA medium were both 100%. The Cefoxitin disc diffusion method had the same sensitivity and specificity as the PCR method for detecting the mecA gene. For MRSA detection, the Cefoxitin disc diffusion method can be employed as an alternative to PCR.

✅ The results showed that 47% and 43% of the isolated samples were resistant to erythromycin and clindamycin, respectively. The prevalence of isolates with erythromycin resistance and induction resistance to clindamycin was approximately 38% and total induction resistance to clindamycin was 12%. The results indicate that antibiogram tests are required to identify induced resistance to clindamycin and to inform physicians about how to prescribe antibiotics in the treatment of infections caused by S. aureus.

✅ No mutations showed amino acid changes. We propose that the DtxR protein is conserved among bacterial strains isolated from Jakarta.

✅ For the last few years, antibiotic resistance has become one of the major concerns within medical society. On one hand, pathogens have mostly acquired resistance against the major conventional antibiotics used in the treatment of microbial infections. These included even first-line antibiotics, which are critical in the treatment of severe infections. This catastrophic situation has occurred due to the extensively irresponsible use of antibiotics in humans and veterinary medicines, agriculture, aquaculture and animal breeding.

✅ Pandemic – this word we learned in our community medicine and public health chapters during medical school. Till 2019 November, many people have even not heard about the pandemic but after the SARS CoV-2 pandemic occurred and the whole world has now faced it. SARS CoV-2 (COVID-19) was first notified in Wuhan city of China and it spread all over the world very rapidly.