year 17, Issue 4 (July - August 2023)                   Iran J Med Microbiol 2023, 17(4): 488-491 | Back to browse issues page

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Muntari J, Pango F, Mappangara I, Khairina Mukhlisah D, Sjahril R. An Adult Woman Diagnosed with Recurrent Rheumatic Fever and Infective Endocarditis with Manifestations of Prolonged Fever and Heart Murmur. Iran J Med Microbiol 2023; 17 (4) :488-491
1- Department of Internal Medicine, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia ,
2- Department of Internal Medicine, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia
3- Department of Cardiology and Vascular Medicine, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia
4- Department of Microbiology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia
Abstract:   (397 Views)

Background and Aim: Rheumatic Fever (RF) is a non-suppurative systemic inflammatory disease with a "delayed autoimmune" caused by Group A streptococcal infections. Inadequate RF treatment causes recurrent RF which is a predisposing factor for Infective Endocarditis.
Case Presentation: A 39-year-old woman was admitted to the hospital with chief complaints of intermittent fever since one month ago, shortness of breath during strenuous activities, weight loss, and easy fatigue. Heart examination palpable thrill, grade 3/6 systolic murmur at apex. Laboratory results were Hb 9.4 g/dl, ESR I: 61 mm, ESR II: 159 mm, ASTO 2563 IU/ml, and CRP 8.9 mg/l. Results of Transthoracic echocardiography revealed vegetation on the posterior mitral leaflet measuring 2.09 x 0.7 and blood culture identified Streptococcus alactolyticus.
Conclusion: Patients diagnosed with recurrent rheumatic fever and infective endocarditis received empirical antibiotic therapy for 2 weeks and corticosteroids, after follow-up the patient experienced clinical improvement and echocardiography showed reduced vegetation size.

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Type of Study: Case report Article | Subject: Medical Bacteriology
Received: 2023/01/16 | Accepted: 2023/05/28 | ePublished: 2023/09/27

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