year 6, Issue 4 (Winter 2013)                   Iran J Med Microbiol 2013, 6(4): 40-50 | Back to browse issues page

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Ghaffari M, Moaddab R, Rafi A, Roshdi Maleki M. Study of Group A -Hemolytic Streptococci Colonization and Resistance Drug of Isolates on 12-14 Year Old Healthy Students of Aras Free Zone Schools. Iran J Med Microbiol. 2013; 6 (4) :40-50
1- Department of microbiology, Faculty of Basic Medical Science, Zanjan Branch, Islamic Azad University, Zanjan, Iran
2- Pramedical faculty and center for TB and pulmonary Diseases, Tabriz University of Medical Sciences.
3- Department of microbiology, Islamic Azad University Malekan Branch, Malekan, Iran
Abstract:   (28898 Views)
Background and objectives: Group A β-Hemolytic Streptococci are the most prevalent pathogenic bacteria that can cause rheumatic fever and acute glomerulonephritis in adolescents so its correct diagnosis and treatment is very important. This study was done with multi stage random sampling method between threehundred 12-14 year old healthy students in Aras Free Zone guidance schools.
Material and Methods :Sixty seven group A β-Hemolytic Streptococcus (GABHS) strains were isolated and were tested with disc diffusion method against sixteen antibiotics including Penicillin, Erythromycin and some second line drugs such as Amoxicillin, Ampicillin, Coamoxiclav, Tobramycin, Gentamicin, Clindamycin, Vancomycin, Tetracycline, Cotrimoxazole, Cloxacillin, Cephalothin, Cephalaxin, Cefazolin, Cefixime.
Results: This study indicated that of 300 students, %22 were healthy carriers ofGABHS. Of 67 healthy carriers, 17 cases (%27) were female students of first base class thatwas the highest rate, whereas 4 cases (%8.5) were female students of second base class that was the lowest rate.
Conclusion: All of GABHS strains (%100) were sensitive to Penicillin and resistance to Cotrimoxazole and Clavulanic acid were detected up to %92 and %89 respectively. Our results showed that prescription of second line drugs must be prescripted more cautiously. Key words:
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Type of Study: Original | Subject: Medical Bacteriology
Received: 2013/11/6 | Accepted: 2013/11/11 | ePublished: 2013/11/11

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