year 13, Issue 2 (May - June 2019)                   Iran J Med Microbiol 2019, 13(2): 89-101 | Back to browse issues page


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Asadi N, Hazrati Tappeh K, Yousefi E, Khademvatan S. Differentiation of prevalent parasite from artifacts in parasitology laboratory. Iran J Med Microbiol. 2019; 13 (2) :89-101
URL: http://ijmm.ir/article-1-842-en.html
1- Department of Parasitology and Mycology, Center for Cellular and Molecular Research, Faculty of Medicine, Urmia University of Medical Sciences, Iran
2- Department of Parasitology and Mycology, School of public health, Tehran University of Medical Sciences, Iran
3- Department of Parasitology and Mycology, Center for Cellular and Molecular Research, Faculty of Medicine, Urmia University of Medical Sciences, Iran , khademvatan@yahoo.com
Abstract:   (5076 Views)
One of the common problems in the medical parasitology laboratory is the differentiation of parasites from other elements in the stool and body fluids so-called "artifacts". Artifacts generally referred to living or abiotic agents that embedded in the clinical sample and may misleading the lab because of their similarity to parasitic organisms. Artifacts are an integral part of the diagnosis process and they are cause of common misdiagnosis in the laboratory.
Their differentiation from pathogenic parasitic agents is done by proper diagnosis, which leads to proper treatment of parasitic infections. As usually an inexperienced technician often misdiagnosed a yeast or other plant cell as amoeba or considers a platelet as a malaria parasite, it may be unsuccessful to identify parasitic organisms that really exist in the stool sample.
The major forms that cause confusion and misdiagnosis in parasitology laboratory are spores, fat droplets, yeast, red blood cells, and macrophages.Compared with other parts of the medical laboratory, in parasitology lab less attention observe  to this problem. The consequence is the reporting of false positive results, incorrect treatment, and patient injury.
 Identifying, introducing, and differentiating artifacts for laboratory personnel, especially inexperienced, are an important factor in accurate diagnosis. In the present study, key diagnostic points of parasitic organisms and artifacts have been categories.
Full-Text [PDF 1903 kb]   (1952 Downloads)    
Type of Study: Review | Subject: Medical Parasitology
Received: 2018/06/11 | Accepted: 2019/08/14 | ePublished: 2019/09/15

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