year 5, Issue 4 (Winter 2012)                   Iran J Med Microbiol 2012, 5(4): 52-58 | Back to browse issues page

XML Persian Abstract Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

vaez H, khosravi S, soleymani E. Antibiotic resistance pattern of common etiological agents of bloodstream infections isolated from patients. Iran J Med Microbiol. 2012; 5 (4) :52-58
1- Department of microbiology ,Golestan university of medical science ,
2- Besat hospital, Microbiology laboratory
3- Besat hospital,Pathobiology laboratory
Abstract:   (12834 Views)
Background and objective: Bloodstream infections (BSI) are dangerous and if not treated appropriately will be accompanied by high mortality. the aim of this study was to determine the frequency of different etiological agents of BSI and their resistance to commonly used antibiotics.
Material and Method: This study performed by 129 positive blood culture samples collected during 2009 to 2010 from patients of tehran besat hospital. Antibiotic susceptibility testing was performed by using disk diffusion method as per clinical and laboratory standards institu (CLSI) guideline. Data analysed by Chi-square test and SPSS soft ware. P value of <0.05 was determined as significant.
Results: The most common causes of BSI were coagulase-negative staphylococcus (CONS) and E.coli 45(34.9%), 38(29.5%) respectively. Infections with proteus vulgaris was rare 2 (1.6%). Prevalence of gram negative infections in comparison with gram positive infections was (1.58:1). The highest resistance was demonstrated as: Penicillin 73.6% - Ampicillin 66.6% -Tetracyclin 58.9%. The highest susceptibility was demonstrated as Gentamicin and Imipenem 68.3%,65.9% respectively.
Conclusion: BSI caused by gram negative bacteria is 1.5 fold more than gram positive bacteria. In our hospital CONS and E.coli are more common etiological agents of BSI (64% of all infections). Vancomycin are suitable antibiotic for treatment of CONA and S.aureus infections.
Full-Text [PDF 415 kb]   (7304 Downloads)    
Type of Study: Original Research Article | Subject: Antibiotic Resistance
Received: 2014/01/4 | Accepted: 2014/01/4 | ePublished: 2014/01/4

Add your comments about this article : Your username or Email:

Send email to the article author

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2022 CC BY-NC 4.0 | Iranian Journal of Medical Microbiology

Designed & Developed by : Yektaweb | Publisher: Farname Inc