year 13, Issue 3 (July - August 2019)                   Iran J Med Microbiol 2019, 13(3): 210-219 | Back to browse issues page

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Yazdani M, Jookar kashi F, Dashti zadeh Z. Evaluation of Antimicrobial and Antioxidant Activity of Essential Oil of Mentha piperita L.. Iran J Med Microbiol. 2019; 13 (3) :210-219
1- Faculty of Chemistry, University of Kashan, Kashan, Iran
2- Department of Cell and Molecular Biology , Faculty of Chemistry, University of Kashan, Kashan, Iran ,
Abstract:   (6051 Views)
Background and Aims: Increasing drug resistance to antibiotics in most bacteria has led to the development of natural antimicrobial compounds. Peppermint (Mentha piperita L.) is one of the most widely used herbs that has many therapeutic effects. The purpose of this study is the evaluation of antimicrobial and antioxidant activity of essential oil of Mentha piperita L.
Materials and Methods: : In this study, after collecting and drying the leaves, essential oils of the plant was extracted using a solvent-free microwave extraction. The compounds of essential oil were identified by the GC-MS (Gas chromatography-mass spectrometry). The effect of antioxidant was determined by beta-carotene test and antimicrobial activity was carried using agar-dilution method also, the minimum inhibitory concentration (MIC) value was evaluated.
Results & Discussion: Menthol, Menthofuran, and 1S-Neomenthyl acetate were the major compounds of essential oil of Mentha piperita L. collected from Marivan, respectively; menthol is the main compound of essential oil. The essential oil was more effective on gram-positive bacteria (Staphylococcus epidermidis, Bacillus subtilis, Staphylococcus aureus) and gram negative (Shigella dysenteriae, Klebsiella pneumonia) also had a good antioxidant activity compared to the standard BHT (butylated hydroxytoluene).Due to its relatively good antimicrobial and antioxidant properties, it can be used in the pharmaceutical and food industries.
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Type of Study: Brief Original Article | Subject: Antimicrobial Substances
Received: 2018/07/9 | Accepted: 2019/08/14 | ePublished: 2019/11/22

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