year 11, Issue 5 (November - December 2017)                   Iran J Med Microbiol 2017, 11(5): 90-97 | Back to browse issues page

XML Persian Abstract Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Sameni F, Zadeh Modarees S, Dabiri H. Prevalence of Chlamydia Trachomatis, Mycoplasma Genitalium and Neisseria Gonorrhea in Infertile Females Referred to Mahdieh Hospital in Tehran . Iran J Med Microbiol. 2017; 11 (5) :90-97
1- Department of Microbiology, Faculty of Advanced Sciences & Technology, Pharmaceutical Sciences Branch, Islamic Azad University, Tehran, Iran ,
2- Department of Gynecology & Obstetric, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
3- Department of Clinical Microbiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran , Iran
Abstract:   (5681 Views)

Background and Aims: Infertility rate has increased by 50% during the last two decades in Iran. There are several factors affecting infertility among women and men, amongst which infections have gained a lot of attentions recently. Given the high percentage of infertility in Iran, the present study has aimed to investigate the prevalence of Chlamydia trachomatis, Mycoplasma genitalium and Neisseria gonorrhea amongst infertile women referring to a hospital in Tehran, Iran.
Materials and Methods: In the current descriptive study, 65 infertile women referring to Mahdieh Hospital in Tehran during 2016-2017 were included and two vaginal swabs and a questionnaire were taken for each patient. In the laboratory, DNA extraction using kit and PCR using specific primers were carried out.
Results: Of the 65 vaginal swab specimens, 21 (32%) had bacterial infection and 44 (68%) had no bacterial infections, and 2 (3%) had the mixed infection. The prevalence of C. trachomatis, M. genitalium and N. gonorrhea were 9 (13.8%), 11 (16.9%) and 4 (6.2%) isolates, respectively. There was no relationship between history of abortion, use of oral contraceptive pills, education or age, with the prevalence of bacterial infections.
Conclusions: Based on the results of this study, M. genitalium, N.gonorrhea, and C.trachomatis were quite prevalent among infertile females and it can, therefore, be concluded that on-time control and treatment of infections caused by these organisms, together with other factors, could be important in prevention and treatment of womenchr('39')s infertility and the community’s health.

Full-Text [PDF 769 kb]   (1219 Downloads)    
Type of Study: Original | Subject: Medical Bacteriology
Received: 2017/07/11 | Accepted: 2017/09/24 | ePublished: 2017/11/20

1. Sadock B, Kaplan SV. Sadocks Synopsis of Psychiatry. 9th eds. Philadelphia: Williams & Wilkins publisher; 2003.
2. Sharma S, Mittal S, Aggarwal P. Management of infertility in low resource countries. BJOG 2009; 116:77-83. [DOI] [PubMed]
3. Thoma M, McLain A, Louis J, King R, Trumble A, Sundaram R et al. Prevalence of infertility in the United States as estimated by the current duration approach and a traditional constructed approach.Fertil Steril 2013;99(5):1324-1331. [DOI] [PubMed]
4. Thonneau P, Spira A. Prevalence of infertility: international data and problems of measurement. Eur J Obstet Gynecol Reprod Biol 1991;38(1):43-52. [DOI]
5. Inhorn MC. Global infertility and the globalization of new reproductive technologies: illustrations from Egypt. Soc Sci Med 2003;56(9):1837-51. [DOI]
6. Dutta S, Guha R. A clinicoanatomical study on the common etiological factors pertaining to primary infertility in females using some common investigative procedures. J Anat Soc India 2007;56(2):14-7.
7. Rutstein SO, Iqbal HS. Infecundity, Infertility, and Childlessness in Developing Countries. DHS Comparative Reports No. 9. Geneva: ORC Macro and the World Health Organization press;2004.
8. Cooper SL, Glazer ES. Beyond Infertility: the new paths to parenthood. 1th ed. Mishawaka (IN): Lexington Books publisher; 1994.
9. Marrs R, Block L, Silverman K. Dr. Richard Marrs' fertility book. 1th ed. New York (NY): Delacorte Press; 1997.
10. Karimpour AA, Esmaeelnezhad Moghadam A, Moslemizadeh N, Mousanezhad N, Peyvandi S, Gahandar M. Incidence and main causes of infertility in patients attending the infertility center of Imam khomeini hospital in 2002-2004. JMUMS 2005;15(49):44-9.
11. Mousavi A, Farhadifar F, Mirnejad R, Ramazanzadeh R. Detection of genital mycoplasmal infections among infertile females by multiplex PCR. Iran J Microbiol 2014;6(6):398-403. [PubMed]
12. Hull M, Glazener C, Kelly N, Conway D, Foster P, Hinton R, Population study of causes, treatment, and outcome of infertility. Br Med J 1985;291(6510):1693-7. [DOI]
13. Gdoura R, Kchaou W, Chaari C, Znazen A, Keskes L, Rebai T, Ureaplasma urealyticum, Ureaplasma parvum, Mycoplasma hominis and Mycoplasma genitalium infections and semen quality of infertile men. BMC Infect Dis 2007;7(1):1. [DOI] [PubMed]
14. Che Y, Cleland J. Infertility in Shanghai: prevalence, treatment seeking and impact. J Obstet Gynaecol 2002;22(6):643-8. [DOI] [PubMed]
15. Ghosh M, Choudhuri S, Ray RG, Bhattacharya B, Bhattacharya S. Association of Genital Chlamydia trachomatis Infection with Female Infer-tility, Study in a Tertiary Care Hospital in Eastern India. Open Microbiol J 2015;9:110. [DOI] [PubMed]
16. Adamson PC, Krupp K, Freeman AH, Klausner JD, Reingold AL, Madhivanan P. Prevalence & correlates of primary infertility among young women in Mysore, India. Indian J Med Res 2011;134(4):440. [PubMed]
17. Vahidi S, Ardalan A, Mohammad K. Prevalence of primary infertility in the Islamic Republic of Iran in 2004-2005. Asia Pac J Public Health 2009;21(3):287-93. [DOI] [PubMed]
18. Baruti M, Ramazni F, Heidari S, Khalajabadi F, Mohamad K. Primery infertility in Tehran based on marriage age. Hakim 2001;15(2):88-93.
19. Abbasi-Shavazi MJ, McDonald P, Hosseini-Chavoshi M. The fertility transition in Iran, Revolution and Reproduction: Springer; 2009. [DOI] [PubMed]
20. Okonofua FE, Snow RC, Alemnji G, Okoruwa A, Ijaware C. Serological and clinical correlates of gonorrhoea and syphilis in fertile and infertile Nigerian women. Genitourin Med 1997;73(3):194-7. [DOI]
21. Imudia AN, Detti L, Puscheck EE, Yelian FD, Diamond MP. The prevalence of ureaplasma urealyticum, mycoplasma hominis, chlamydia trachomatis and neisseria gonorrhoeae infections, and the rubella status of patients undergoing an initial infertility evaluation. J Assist Reprod Genet 2008;25(1):43-6. [DOI] [PubMed]
22. Grześko J, Elias M, Mączyńska B, Kasprzykowska U, Tłaczała M, Goluda M. Occurrence of Mycoplasma genitalium in fertile and infertile women. Fertil Steril 2009;91(6):2376-80. [DOI] [PubMed]
23. Xu J, Liu C. Chlamydia and mycoplasma infection in genital tracts of 416 infertile female patients and drug sensitivity. Chinese Journal of Nosocomiology. 2010;20(18):2884-5.
24. Hassanzadeh P, Mardaneh J, Motamedifar M. Conventional Agar-Based Culture Method, and Nucleic Acid Amplification Test (NAAT) of the cppB Gene for Detection of Neisseria gonorrhea in Pregnant Women Endocervical Swab Specimens. Iran Red Crescent Med J 2013;15(3):207-11. [DOI] [PubMed]
25. Nwankwo E, Magaji N. Prevalence of Chlamydia trachomatis infection among patients attending infertility and sexually transmitted diseases clinic (STD) in Kano, North Western Nigeria. Afr Health Sci 2014;14(3):672-8. [DOI] [PubMed]

Add your comments about this article : Your username or Email:

Send email to the article author

© 2021 All Rights Reserved | Iranian Journal of Medical Microbiology

Designed & Developed by : Yektaweb | Publisher: Farname Inc