year 18, Issue 6 (November - December 2024)                   Iran J Med Microbiol 2024, 18(6): 398-410 | Back to browse issues page


XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Cabuhat K S P, Ong C J N, Lee M Y S, Mallari R, Balilla J, Espiritu L M. Assessment of Knowledge, Attitude, and Behavior (KAB) Associated With the Use of Antibiotics and Presence of Antibiotic Resistance Among STEM Students in the Philippines: A Cross-sectional Study. Iran J Med Microbiol 2024; 18 (6) :398-410
URL: http://ijmm.ir/article-1-2295-en.html
1- Department of Biology, College of Science, De La Salle University, Manila, Philippines & Department of Basic Education, La Consolacion University Philippines, Malolos, Bulacan, Philippines
2- Department of Biology, College of Science, De La Salle University, Manila, Philippines , christian_joseph_ong@dlsu.edu.ph
3- Department of Biology, College of Science, Bulacan State University, Malolos, Bulacan, Philippines
4- Department of Basic Education, La Consolacion University Philippines, Malolos, Bulacan, Philippines
5- Department of Mathematics, College of Science, Bulacan State University, Malolos, Bulacan, Philippines
6- Department of Biology, College of Science, De La Salle University, Manila, Philippines
Abstract:   (818 Views)

Background and Aim: Misuse and overuse of antibiotics fuel the development of antibiotic resistance. Therefore, these drugs have become ineffective and antimicrobial resistance has emerged. The study aimed to assess the current knowledge, attitude, and behavior (KAB) of the Science, Technology, Engineering, and Mathematics (STEM) students in one of the selected private universities in Malolos, Bulacan, Philippines, concerning antibiotic resistance and usage.
Materials and Methods: This cross-sectional study surveyed 245 Grade 12 STEM students in Malolos, Bulacan, Philippines using KAB survey questionnaires to assess the antibiotic use and resistance in society. This group was selected as they will be future deciding authorities to educate people. The survey assessed students' KAB regarding the use of antimicrobial drugs in clinical settings.
Results: The study revealed low level of students’ knowledge about antibiotic usage and the presence of antibiotic resistance. They incorrectly believed that antibiotics can be used as prophylaxis and can be bought without prescription. Additionally, they believed that antibiotics can speed up the recovery of colds and coughs. On the attitude level, less than 60% agreed that antibiotic resistance is a global public health concern. Additionally, 3 out of 7 statements in the behavior section were incorrectly answered, indicating low level of behavior.
Conclusion: The findings indicate a need to promote awareness about proper antibiotic usage that may provide helpful additional evidence to develop a successful framework for improving antibiotic information dissemination, particularly in academic institutions.

Full-Text [PDF 818 kb]   (206 Downloads) |   |   Full-Text (HTML)  (132 Views)  
Type of Study: Original Research Article | Subject: Antibiotic Resistance
Received: 2024/05/15 | Accepted: 2024/10/23 | ePublished: 2025/01/29

References
1. Adedeji WA. The treasure called antibiotics. Ann Ib Postgrad Med. 2016;14(2):56-7. [PMID] [PMCID]
2. Hutchings MI, Truman AW, Wilkinson B. Antibiotics: past, present and future. Curr Opin Microbiol. 2019;51:72-80. [DOI:10.1016/j.mib.2019.10.008] [PMID]
3. Dejene H, Birhanu R, Tarekegn ZS. Knowledge, attitude and practices of residents toward antimicrobial usage and resistance in Gondar, Northwest Ethiopia. One Health Outlook. 2022;4(1):10. [DOI:10.1186/s42522-022-00066-x] [PMID] [PMCID]
4. Boonyasiri A, Tangkoskul T, Seenama C, Saiyarin J, Tiengrim S, Thamlikitkul V. Prevalence of antibiotic resistant bacteria in healthy adults, foods, food animals, and the environment in selected areas in Thailand. Pathog Glob Health. 2014;108(5):235-45. [DOI:10.1179/2047773214Y.0000000148] [PMID] [PMCID]
5. Prestinaci F, Pezzotti P, Pantosti A. Antimicrobial resistance: a global multifaceted phenomenon. Pathog Glob Health. 2015;109(7):309-18. [DOI:10.1179/2047773215Y.0000000030] [PMID] [PMCID]
6. Pormohammad A, Nasiri MJ, Azimi T. Prevalence of antibiotic resistance in Escherichia coli strains simultaneously isolated from humans, animals, food, and the environment: a systematic review and meta-analysis. Infect Drug Resist. 2019;12:1181-97. [DOI:10.2147/IDR.S201324] [PMID] [PMCID]
7. Derakhshan S, Navidinia M, Haghi F. Antibiotic susceptibility of human-associated Staphylococcus aureus and its relation to agr typing, virulence genes, and biofilm formation. BMC Infect Dis. 2021;21(1):627. [DOI:10.1186/s12879-021-06307-0] [PMID] [PMCID]
8. Center for Disease Control and Prevention. 2019 AR Threats Report. 2013. [Accessed 29 Jan 2025]. Available from: [https://www.cdc.gov/antimicrobial-resistance/data-research/threats/]
9. de Kraker ME, Stewardson, AJ, Harbarth S. Will 10 Million People Die a Year due to Antimicrobial Resistance by 2050?. PLoS Med. 2016;13(11):e1002184. [DOI:10.1371/journal.pmed.1002184] [PMID] [PMCID]
10. Marzan M, Islam DZ, Lugova, H. Knowledge, Attitudes, and Practices of Antimicrobial Uses and Resistance Among Public University Students in Bangladesh. Infect Drug Resist. 2021;14:519-33. [DOI:10.2147/IDR.S289964] [PMID] [PMCID]
11. Higuita-Gutiérrez LF, Roncancio Villamil GE, Jiménez Quiceno JN. Knowledge, attitude, and practice regarding antibiotic use and resistance among medical students in Colombia: a cross-sectional descriptive study. BMC Public Health. 2020;20:1861 [DOI:10.1186/s12889-020-09971-0] [PMID] [PMCID]
12. Islahudin F, Tamezi AM, Shah NM. Knowledge, Attitudes and Practices about Antibiotic Use among the General Public in Malaysia. Southeast Asian J Trop Med Public Health. 2014;45(6):1474-82.
13. Lim JM, Duong MC, Cook AR, Hsu LY, Tam CC. Public knowledge, attitudes and practices related to antibiotic use and resistance in Singapore: a cross-sectional population survey. BMJ Open. 2021;11(9):e048157. [DOI:10.1136/bmjopen-2020-048157] [PMID] [PMCID]
14. Askarian M, Maharlouie N. Irrational Antibiotic Use among Secondary School Teachers and University Faculty Members in Shiraz, Iran. Int J Prev Med. 2012;3(12):839-45. [DOI:10.4103/2008-7802.104854] [PMID] [PMCID]
15. Di Gennaro F, Marotta C, Amicone M, Bavaro DF, Bernaudo F, Frisicale EM, et al. Italian young doctors' knowledge, attitudes and practices on antibiotic use and resistance: A national cross-sectional survey. J Glob Antimicrob Resist. 2020;23:167-73. [DOI:10.1016/j.jgar.2020.08.022] [PMID]
16. Ashraf S, Ashraf S, Ashraf M, Imran MA, Choudhary ZA, Hafsa HT, et al. Knowledge, attitude, and practice of clinicians about antimicrobial stewardship and resistance among hospitals of Pakistan: a multicenter cross-sectional study. Environ Sci Pollut Res Int. 2022;29(6):8382-92. [DOI:10.1007/s11356-021-16178-2] [PMID] [PMCID]
17. Shrestha R. Knowledge, Attitude and Practice on Antibiotics Use and its Resistance among Medical Students in A Tertiary Care Hospital. JNMA: J Nepal Med Assoc. 2019;57(216):74-9. [DOI:10.31729/jnma.4224] [PMID] [PMCID]
18. Battah M, Halboup A, Othman G, Mansoure AA, Sulaiman SA, Ali F, et al. Knowledge, attitude, and practice of antibiotic use and its resistance among undergraduate students at the University of Science and Technology, Sana’a, Yemen. J Hunan Univ Nat Sci. 2021;48(11):34-43.
19. Sunusi LS, Awad MM, Hassan NM, Isa CA. Assessment of knowledge and attitude toward antibiotic use and resistance among students of International University of Africa, medical complex, Sudan. Glob Drugs Ther. 2019;4:1-6. [DOI:10.15761/GDT.1000171]
20. Crucis PM, Encarnacion EM, Lapuz AM, Magno ME, Pantia JS, Solis LA. Knowledge, attitude and practices on the use of antimicrobials among residents in Towerville Phase 5, Barangay Minuyan, San Jose del Monte, Bulacan, Philippines: A Questionnaire Survey. J Asian Ass Sch Pharm. 2019;8:64-71.
21. Nepal A, Hendrie D, Robinson S, Selvey LA. Knowledge, attitudes and practices relating to antibiotic use among community members of the Rupandehi District in Nepal. BMC Public Health. 2019;19(1):1558. [DOI:10.1186/s12889-019-7924-5] [PMID] [PMCID]
22. Chapot L, Sarker MS, Begum R, Hossain D, Akter R, Hasan MM, et al. Knowledge, Attitudes and Practices Regarding Antibiotic Use and Resistance among Veterinary Students in Bangladesh. Antibiotics. 2021;10(3):332. [DOI:10.3390/antibiotics10030332] [PMID] [PMCID]
23. Naing S, van Wijk M, Vila J, Ballesté-Delpierre C. Understanding Antimicrobial Resistance from the Perspective of Public Policy: A Multinational Knowledge, Attitude, and Perception Survey to Determine Global Awareness. Antibiotics. 2021;10(12):1486. [DOI:10.3390/antibiotics10121486] [PMID] [PMCID]
24. Raosoft Inc. Sample size calculator. 2025. [Accessed 29 Jan 2025]. Available from: [http://www.raosoft.com/samplesize.html]
25. Huang Y, Gu J, Zhang M, Ren Z, Yang W, Chen Y, et al. Knowledge, attitude and practice of antibiotics: a questionnaire study among 2500 Chinese students. BMC Med Educ. 2013;13:1-9. [DOI:10.1186/1472-6920-13-163] [PMID] [PMCID]
26. El Sherbiny NA, Ibrahim EH, Masoud M. Assessment of knowledge, attitude and behavior towards antibiotic use in primary health care patients in Fayoum Governorate, Egypt. Alex J Med. 2018;54(4):535-40. [DOI:10.1016/j.ajme.2018.06.001]
27. Goss-Sampson MA. Statistical Analysis in JASP 0.10: A Guide for Students. 2019. [Accessed 29 Jan 2025]. Available from JASP (Jeffreys’s Amazing Statistics Program): [https://jasp-stats.org/jasp-materials]
28. Lubwama M, Onyuka J, Ayazika KT, Ssetaba LJ, Siboko J, Daniel O, et al. Knowledge, attitudes, and perceptions about antibiotic use and antimicrobial resistance among final year undergraduate medical and pharmacy students at three universities in East Africa. PLoS One. 2021;16(5):e0251301. [DOI:10.1371/journal.pone.0251301] [PMID] [PMCID]
29. Al-Taani GM, Al-Azzam S, Karasneh RA, Sadeq AS, Mazrouei NA, Bond SE, et al. Pharmacists' Knowledge, Attitudes, Behaviors and Information Sources on Antibiotic Use and Resistance in Jordan. Antibiotics. 2022;11(2):175. [DOI:10.3390/antibiotics11020175] [PMID] [PMCID]
30. Vijay D, Bedi JS, Dhaka P, Singh R, Singh J, Arora AK, et al. Knowledge, Attitude, and Practices (KAP) Survey among Veterinarians, and Risk Factors Relating to Antimicrobial Use and Treatment Failure in Dairy Herds of India. Antibiotics. 2021;10(2):216. [DOI:10.3390/antibiotics10020216] [PMID] [PMCID]
31. Shahpawee NS, Chaw LL, Muharram SH, Goh HP, Hussain Z, Ming LC. University Students' Antibiotic Use and Knowledge of Antimicrobial Resistance: What Are the Common Myths?. Antibiotics. 2020;9(6):349. [DOI:10.3390/antibiotics9060349] [PMID] [PMCID]
32. Poyongo BP, Sangeda RZ. Pharmacists' Knowledge, Attitude and Practice Regarding the Dispensing of Antibiotics without Prescription in Tanzania: An Explorative Cross-Sectional Study. Pharmacy. 2020;8(4):238. [DOI:10.3390/pharmacy8040238] [PMID] [PMCID]
33. Jairoun A, Hassan N, Ali A, Jairoun O, Shahwan M, Hassali M. University students' knowledge, attitudes, and practice regarding antibiotic use and associated factors: a cross-sectional study in the United Arab Emirates. Int J Gen Med. 2019;12:235-46. [DOI:10.2147/IJGM.S200641] [PMID] [PMCID]
34. Cambaco O, Alonso Menendez Y, Kinsman J, Sigaúque B, Wertheim H, Do N, et al. Community knowledge and practices regarding antibiotic use in rural Mozambique: where is the starting point for prevention of antibiotic resistance?. BMC Public Health. 2020;20(1):1183. [DOI:10.1186/s12889-020-09243-x] [PMID] [PMCID]
35. Wu-Wu JW, Guadamuz-Mayorga C, Oviedo-Cerdas D, Zamora WJ. Antibiotic Resistance and Food Safety: Perspectives on New Technologies and Molecules for Microbial Control in the Food Industry. Antibiotics. 2023;12(3):550. [DOI:10.3390/antibiotics12030550] [PMID] [PMCID]
36. Min S, Zhou Y, Sun Y, Ye J, Dong Y, Wang X, et al. Knowledge, attitude, and practice associated with antimicrobial resistance among medical students between 2017 and 2022: A survey in East China. Front Public Health. 2022;10:1010582. [DOI:10.3389/fpubh.2022.1010582] [PMID] [PMCID]
37. Virmani S, Nandigam M, Kapoor B, Makhija P, Nair S. Antibiotic use among health science students in an Indian university: A cross sectional study. Clin Epidemiol Glob Health. 2017;5(4):176-9. [DOI:10.1016/j.cegh.2017.04.005]
38. Haque M, Rahman NA, McKimm J, Kibria GM, Azim Majumder MA, Haque SZ, et al. Self-medication of antibiotics: investigating practice among university students at the Malaysian National Defence University. Infect Drug Resist. 2019;12:1333-51. [DOI:10.2147/IDR.S203364] [PMID] [PMCID]
39. World Health Organization (WHO). SInternational organizations unite on critical recommendations to combat drug-resistant infections and prevent staggering number of deaths each year. 2019. [Accessed 29 Jan 2025]. Available from: [https://www.who.int/news/item/29-04-2019-new-report-calls-for-urgent-action-to-avert-antimicrobial-r]
40. Soto SM. Antibiotic Resistance in Bacterial Pathogens. Antibiotics. 2023;12(3):451. [DOI:10.3390/antibiotics12030451] [PMID] [PMCID]
41. Kandasamy G, Sivanandy P, Almaghaslah D, Khobrani M, Chinnadhurai M, Vasudevan R, et al. Knowledge, attitude, perception and practice of antibiotics usage among the pharmacy students. Int J Clin Pract. 2020;74(11):e13599. [DOI:10.1111/ijcp.13599]
42. Alhomoud F, Almahasnah R, Alhomoud FK. “You could lose when you misuse”–factors affecting over-the-counter sale of antibiotics in community pharmacies in Saudi Arabia: a qualitative study. BMC Health Serv Res. 2018;18:915. [DOI:10.1186/s12913-018-3753-y] [PMID] [PMCID]
43. Gaygısız Ü, Lajunen T, Gaygısız E. Community Use of Antibiotics in Turkey: The Role of Knowledge, Beliefs, Attitudes, and Health Anxiety. Antibiotics. 2021;10(10):1171. [DOI:10.3390/antibiotics10101171] [PMID] [PMCID]
44. Memon I, Alrashid AA, Alshammari HS, Rehman DE, Feroz Z, Nagro A, et al. Assessing the Effects of Basic Medical Science Courses on the Knowledge and Attitude towards Antibiotic Usage among Pre-Professional Students in Saudi Arabia. Pharmacy. 2021;9(2):108. [DOI:10.3390/pharmacy9020108] [PMID] [PMCID]
45. Alex IO. Knowledge of antibiotic use and resistance among students of a medical school in Nigeria. Malawi Med J. 2019;31(2):133-7. [DOI:10.4314/mmj.v31i2.5] [PMID] [PMCID]
46. U.S. Food and Drug Administration (US FDA). Don’t Be Tempted to Use Expired Medicines. 2021. [Accessed 29 Jan 2025]. Available from: [https://www.fda.gov/drugs/special-features/dont-be-tempted-use-expired-medicines]
47. Alkhalifah HM, Alkhalifah KM, Alharthi AF, Elzahrany YR, Aljuhani MA. Knowledge, attitude and practices towards antibiotic use among patients attending Al Wazarat health center. Fam Med and Prim Care. 2022;11(4):1299-307. [DOI:10.4103/jfmpc.jfmpc_1431_21] [PMID] [PMCID]
48. Smith DR, Dolk FC, Smieszek T, Robotham JV, Pouwels KB. Understanding the gender gap in antibiotic prescribing: a cross-sectional analysis of English primary care. BMJ Open. 2018;8(2):e020203. [DOI:10.1136/bmjopen-2017-020203] [PMID] [PMCID]

Add your comments about this article : Your username or Email:
CAPTCHA

Send email to the article author


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2025 CC BY-NC 4.0 | Iranian Journal of Medical Microbiology

Designed & Developed by : Yektaweb | Publisher: Farname Inc