year 17, Issue 5 (September - October 2023)                   Iran J Med Microbiol 2023, 17(5): 606-612 | Back to browse issues page


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Othman Ahmad R, Ahmadi A, Bahmani N, Taherpour A. Application of WHONET in the Analysis of Pseudomonas aeruginosa Resistance to Imipenem and Meropenem. Iran J Med Microbiol 2023; 17 (5) :606-612
URL: http://ijmm.ir/article-1-2100-en.html
1- Student Research Committee, Kurdistan University of Medical Sciences, Sanandaj, Iran
2- Department of Microbiology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
3- Zoonoses Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran
4- Department of Microbiology, Faculty of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran , rezaeeit93@gmail.com
Abstract:   (540 Views)

Background and Aim: WHONET software is a database for analyzing microbiology data, specifically antibiotic resistance patterns. Pseudomonas aeruginosa is a significant agent of nosocomial infections and has been identified as a critical priority by the World Health Organization (WHO). The aim of this study was to monitor the resistance patterns of imipenem and meropenem over one year (February 2022-February 2023) using WHONET software 2022.
Materials and Methods: A total of 95 P. aeruginosa isolates were obtained from Kowsar Hospital in Sanandaj, Iran. After verification through biochemical tests and 16sRNA PCR, an antibiogram test was performed for each isolate based on The Clinical & Laboratory Standards Institute (CLSI) guidelines. Data were analyzed using WHONET 2022.
Results & Conclusion: Pseudomonas aeruginosa isolates were obtained from 44 females and 51 males. Of all isolates, the WHONET analysis showed that resistance to imipenem and meropenem was 87.4% and 64.2%, respectively. The WHONET database can be an appropriate software for analyzing and monitoring bacterial susceptibility and resistance, especially for critical priority bugs such as P. aeruginosa.

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Type of Study: Brief Original Article | Subject: Antibiotic Resistance
Received: 2023/06/19 | Accepted: 2023/09/21 | ePublished: 2023/11/29

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