Gadyari F, Sattari M, Boroumand M A, Yaghoubi R, Sepehriseresht S, Purgholi L. Detection of Staphylococcus aureus Entrotoxins A to D in clinical strains isolated from burned patients of Tehran Motahari Hospital. Iran J Med Microbiol 2011; 5 (1 and 2) :20-27
URL:
http://ijmm.ir/article-1-173-en.html
1- Department of Microbiology, Islamic Azad University, Jahrom Branch, Jahrom - Iran.
2- Department of Bacteriology, Tarbiat Modares University, Tehran Branch, Tehran - Iran , sattarim@modares.ac.ir
3- Department of Pathology, Tehran Heart Center Hospital, Tehran - Iran
4- Shiraz Transplant Research Center, Namazi Hospital, University of Medical Sciences
Abstract: (18622 Views)
Background and abjectives: Staphylococcus aureus is one of the important Pathogens in
Nosocomial infections. One of the S.aureus toxins is pyrogenic toxins entrotoxins. Some strains
prodused one or more 19 types enterotoxin. The objective of this study is evaluation of
Staphylococcus aureus strains producing entrotoxin genes isolated from burned patients.
Materials and Methods: In this sectional study, by using PCR technique determine entrotoxine
encoding genes sea, seb, sec, sed of 100 isolated samples from burned patients wound of
Motahari Hospital.
Results: The result PCR showed of totally 100 isolated S.aureus, 12% produced sea, 1%
produced seb, 35% produced sec and 3% sed gene . Which 42% of samples produced both
enterotoxins, that 2% produced sea + seb, 32% sea+sec, 2% produced sea + sed and 6%
produced sec + sed.
Conclusion: According to the importance entrotoxins is as superantigen and play clinical role
in emergence of field diseases and also production of this toxin by clinical strains has great
importance that in case of expression of these genes, immediate treatment of infection seems
vital.
Type of Study:
Original Research Article |
Subject:
Molecular Microbiology Received: 2013/11/28 | Accepted: 2013/11/28 | ePublished: 2013/11/28