Sharifi M, Borhan Modjabi K, Salmani M, Farhang R, Mostadjeri A, Alipour Heidary M. Prevalence of antibodies to hepatitis and AIDS viuses among dentists in Qazvin. Iran J Med Microbiol 2008; 2 (2) :55-61
URL:
http://ijmm.ir/article-1-121-en.html
1- Department of Microbiology , School of Medicine, Qazvin University of Medical Sciences , dr_m_sharifi2002@yahoo.com
2- Department of Oral Medicine & Diagnosis, School of Dentistry , Qazvin University ofMedical Sciences
3- Dentist
4- Qazvin Transfusion Center
5- Department of Community Medicine , School of Medicine , Qazvin University of Medical Sciences
Abstract: (36315 Views)
Background and objectives: Hepatitis viruses and Human Immunodeficiency Virus (HIV) are the most
common blood-borne infections transmitted to healthcare workers. This study was performed to determine
the prevalence of antibodies to hepatitis and AIDS viruses among dentists in Qazvin.
Materials and Methods: All dentists in the city of Qazvin were asked to complete a questionnaire and
donate a blood sample for analysis of hepatitis B surface antigen (HBsAg), anti-HBs titer, anti-HCV, and
anti- HIV antibodies by ELISA. Positive samples for anti-HCV, and anti- HIV were assessed by RIBA and
Western blot. Data analysis was carried out through SPSS software and Chi-square test.
Results: From 77 dentists who completed the questionnaire, 74 dentists (93.7%), including 49 general
dentists (63.6%) and 24 specialists(36.4%) supplied blood samples. All blood samples were HBsAg, , antiHCV and anti- HIV negative, and 40 general dentists (83.3%) and 24 specialists (92.3%) have used
complete doses of vaccine. Among dentists, 34 general dentists (69.4%) and 12 specialists (24.9%) have
visited patients suffering with hepatitis ( 1.5 times for general dentists) . Antibody titer in 8 general dentists
(10.8 %) was less than 10 mIU/ml , in 12 dentists(16.2%) was 10-100 mIU/ml in 23 dentists (31.1%) 100-500 mIU/ml and in 31 dentist (41.9%) was more than 500 mIU/ml . This level in 2 general dentists (2.7%)
without prior vaccination was positive (10-500 mIU/ml). Between antibody level and vaccine dose (P= 0.04),
as well as the education status (general and specialist) (P= 0.03 ) there was a significant correlation.
Conclusion: The findings indicate HBsAg,, anti-HCV and anti- HIV are negative. Compliance of
complete doses of vaccine and anti-HBs titers is satisfactory. But, antibody titer without prior vaccination
indicates the continuous risk of HBV infection for dentists and in fact the risk of blood borne pathogens.
There is a correlation between anti-HBs titer with vaccine doses and also with education status. Regarding
with more hepatitic patients visited bygeneral dentists, this group is more exposed to blood borne pathogens
and emphasis the continuous education about control infection and surveillance ofdentists by blood borne
pathogens tests.
Type of Study:
Original Research Article |
Subject:
Medical Virology Received: 2013/11/15 | Accepted: 2013/11/15 | ePublished: 2013/11/15