Salivary Cortisol Associated with Increasing Mutans streptococci Count in Drug Abuser

Yassin, Bilal A.; Al-Mizraqchi, Abbas S.

doi:10.30699/ijmm.17.3.318

year 17, Issue 3 (May - June 2023) Iran J Med Microbiol 2023, 17(3): 318-323 | Back to browse issues page

‎ 10.30699/ijmm.17.3.318

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Yassin B A, Al-Mizraqchi A S. Salivary Cortisol Associated with Increasing Mutans streptococci Count in Drug Abuser. Iran J Med Microbiol 2023; 17 (3) :318-323
URL: http://ijmm.ir/article-1-2077-en.html

Salivary Cortisol Associated with Increasing Mutans streptococci Count in Drug Abuser

Bilal A. Yassin

¹, Abbas S. Al-Mizraqchi²

1- Department of Basic Sciences, College of Dentistry, University of Baghdad, Baghdad, Iraq , bilotb@gmail.com
2- Medical Microbiology, Department of Basic Sciences, College of Dentistry, University of Baghdad, Baghdad, Iraq

Abstract: (1131 Views)

Background and Aim: The aim of this study was to evaluate the relationship between salivary cortisol levels and the viable count of mutans streptococci in drug abusers.
Materials and Methods: The study was conducted from March 2022 to May 2022 and included 86 participants aged between 17 to 30 years, who were equally divided into two groups: cases (n= 43) and controls (n= 43). All participants underwent a urine drug line test to confirm their drug use status. Saliva was collected, and centrifuged at 3000 for 10 min, and the supernatant was stored at -20°C for later estimation of salivary cortisol levels using a Cobas device. The viable count of Mutans streptococci was determined using an identification and culturing method to calculate the colony-forming units per milliliter (CFU/ml).
Results: The drug abusers exhibited a significantly higher concentration of salivary cortisol as compared to the control group. In addition, the cases showed a positive correlation between salivary cortisol levels and the count of Mutans Streptococci. In contrast, the control group demonstrated a negative and non-significant relationship.
Conclusion: The data from the current study indicated a higher concentration of salivary cortisol associated with an increasing count of Mutans streptococci compared to the control group.

Keywords: Mutans Streptococci, Salivary Cortisol, Drug Abuser

Full-Text [PDF 487 kb] (361 Downloads) | | Full-Text (HTML) (236 Views)

Type of Study: Original Research Article | Subject: Medical Bacteriology
Received: 2023/03/28 | Accepted: 2023/04/29 | ePublished: 2023/06/26

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