The Distributions of HCV Genotypes in Hemodialysis Patients in Iraq

Hussein, Nawfal; Al-Obeidy, Eman Sh; Naqid, Ibrahim; Abd, Kais H; Abdulrahman, Shakir

doi:10.30699/ijmm.13.4.279

year 13, Issue 4 (September - October 2019) Iran J Med Microbiol 2019, 13(4): 279-283 | Back to browse issues page

‎ 10.30699/ijmm.13.4.279

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Hussein N, Al-Obeidy E S, Naqid I, Abd K H, Abdulrahman S. The Distributions of HCV Genotypes in Hemodialysis Patients in Iraq. Iran J Med Microbiol 2019; 13 (4) :279-283
URL: http://ijmm.ir/article-1-964-en.html

The Distributions of HCV Genotypes in Hemodialysis Patients in Iraq

Nawfal Hussein¹

, Eman Sh Al-Obeidy²

, Ibrahim Naqid

³, Kais H Abd⁴

, Shakir Abdulrahman¹

1- College of Medicine, University of Zakho, Zakho, Kurdistan region, Iraq
2- Dialysis Center, Baghdad Medical cities, Baghdad, Iraq
3- College of Medicine, University of Zakho, Zakho, Kurdistan region, Iraq , ibrahim.naqid@uoz.edu.krd
4- Duhok Renal Dialysis Center, Duhok, Kurdistan Region, Iraq

Abstract: (3691 Views)

Objectives: The aim of this report was to investigate the genotypes of HCV in patients on regular hemodialysis in Iraq.
Methods: A cross sectional study was conducted to investigate the genotypes of HCV in patients on regular hemodialysis in 7 centers across Iraq. 255 subjects with positive anti-HCV antibodies were recruited in this study.
Results: To confirm the positivity, RTPCR was performed. Amongst all samples, 31% (79/255) was positive by RTPCR. Then, we genotyped all the RTPCR positive samples, it was found that 39/79 (49.4 %) of our samples were typed as HCV genotype 1 including 26 samples (66.7%) as HCV 1a and 13 samples (33.3%) as HCV 1b. HCV genotype 4 was found in 34/79 (43%) of the samples while 6/79 (7.6%) of the samples typed as HCV 3
Conclusions: HCV genotype 1 was the most prevalent genotype followed by genotype 4. Further population-based study is required to investigate the prevalence of HCV genotypes.

Keywords: HCV, Genotypes, Hemodialysis Patients, Iraq

Full-Text [PDF 1070 kb] (1769 Downloads) | | Full-Text (HTML) (1590 Views)

Type of Study: Original Research Article | Subject: Molecular Microbiology
Received: 2019/09/23 | Accepted: 2020/01/19 | ePublished: 2020/01/19

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