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:: year 12, Issue 2 (May - June 2018) ::
Iran J Med Microbiol 2018, 12(2): 0-0 Back to browse issues page
Study of biocompatibility and antibacterial properties of titanium substrates coated with chitosan reinforced with graphene oxide
Shahab Faghihi Dr 1, Mahsa Gheysoor MS2
1- Associate Prof Department of Stem Cell and Reproductive Medicine, National Institute of Genetics and Biotechnology, Tehran, Iran , shahabeddin.faghihi@mail.mcgill.ca
2- MSc Department of Stem Cell and Reproductive Medicine, National Institute of Genetics and Biotechnology, Tehran, Iran
Abstract:   (350 Views)
Aims: In this study graphene oxide based coatings are applied on the titanium substrates in order to improve their biocompatibility and antibacterial properties of titanium substrate.
Methods: Chitosan, graphene oxide and their composites separately are coated on the substrates and their hydrophilicity and roughness are measured using contact angle measurement and atomic force microscopy. The coated substrates are then exposed to MG63 osteoblasts and Staphylococcus aureus in order to evaluate the interactions.
Results: The results show that titanium samples that are coated with chitosan and composites have better surface hydrophilicity and higher roughness compared to other samples and uncoated titanium. Cell adhesion is also improved on the coated substrates. Regarding the antibacterial property the composite coating show the best results.
Conclusion: It is concluded that the titanium substrate which is coated with nanocomposite of graphene oxide and chitosan has higher hydrophilicity and roughness that resulted to enhance biocompatibility and antibacterial property. This may lead to a higher success rate in the application of these substrates in maxillofacial implant surgeries.
Keywords: Titanium, Graphene oxide, Chitosan, Biocompatibility, Antibacterial.
     
Type of Study: Original | Subject: Nanotechnology In Medicine
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Faghihi S, Gheysoor M. Study of biocompatibility and antibacterial properties of titanium substrates coated with chitosan reinforced with graphene oxide. Iran J Med Microbiol. 2018; 12 (2)
URL: http://ijmm.ir/article-1-812-en.html


year 12, Issue 2 (May - June 2018) Back to browse issues page
مجله میکروب شناسی پزشکی ایران Iranian Journal of Medical Microbiology
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