Detection of LMP1 protein in Breast Cancer tissue samples from Fars province hospitals

Shariat, Afsoon

year 11, Issue 1 (March - April 2017) Iran J Med Microbiol 2017, 11(1): 67-74 | Back to browse issues page

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Shariat A. Detection of LMP1 protein in Breast Cancer tissue samples from Fars province hospitals . Iran J Med Microbiol 2017; 11 (1) :67-74
URL: http://ijmm.ir/article-1-590-en.html

Detection of LMP1 protein in Breast Cancer tissue samples from Fars province hospitals

Afsoon Shariat

Department of Microbiology, Faculty of Basic Sciences, Kazerun Branch, Islamic Azad University, Kazerun, Iran , afsoonsh1980@yahoo.com

Abstract: (8675 Views)

Background and Aim: Breast cancer is the most common malignancy among women and Epstein Barr virus could be a reason to develop this cancer. The aim of this study is to evaluate the association between Epstein Barr virus and breast cancer by Immunohistochemical method in Fars province hospitals.

Materials and Methods: This study was carried out in 1390-1395. 80 cases of breast cancer tissue samples were selected from formalin-fixed paraffin embedded blocks from Fars province hospitals and by immunohistochemistry method the expression of the LMP1 viral protein were examined. Data analyzed by SPSS statistical software.

Results: Epstein Barr virus was not detected in the breast cancer tissues and expression of viral protein of LMP1 was not observed in any of the breast cancer specimens by Immunohistochemistry.

Conclusions: The results were shown that Epstein Barr virus may not be associated with breast cancer in Fars province and further studies are needed to determine the relationship between breast cancer virus with a variety of molecular methods.

Keywords: Epstein-Barr virus, Breast cancer, Immunohistochemistry, LMP1 protein

Full-Text [PDF 615 kb] (2379 Downloads)

Type of Study: Original Research Article | Subject: Medical Virology
Received: 2016/07/16 | Accepted: 2016/11/19 | ePublished: 2017/03/16

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