Study of accosiation between male infertility and Neisseria gonorrhoeae and Ureaplasma urealyticum infection

Karimian, Reyhaneh; Roghanian, Rasoul; Etemadifar, Zahra

year 10, Issue 3 (July - August 2016) Iran J Med Microbiol 2016, 10(3): 11-18 | Back to browse issues page

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Karimian R, Roghanian R, Etemadifar Z. Study of accosiation between male infertility and Neisseria gonorrhoeae and Ureaplasma urealyticum infection. Iran J Med Microbiol 2016; 10 (3) :11-18
URL: http://ijmm.ir/article-1-505-en.html

Study of accosiation between male infertility and Neisseria gonorrhoeae and Ureaplasma urealyticum infection

Reyhaneh Karimian¹

, Rasoul Roghanian

², Zahra Etemadifar¹

1- Department of Biology, Faculty of Science, University of Isfahan, Isfahan, Iran
2- Department of Biology, Faculty of Science, University of Isfahan, Isfahan, Iran , R.Roghanian@sci.Ui.Ac.Ir

Abstract: (9031 Views)

Background and Aim: Neisseria gonorrhoeae and Ureaplasma urealyticum are the main cause of genital infections and infertility in both genders. However, there are few studies regarding N. gonorrhoeae in semen samples of infertile men. Therefore, the aim of this study was the prevalence of N. gonorrhoeae and U. urealyticum infection in infertile men.

Materials and Methods: 100 samples were collected from two groups. The first group was 50 samples from men with abnormal semen analysis tests In Isfahan Fertility and Infertility Center and the second was 50 samples from men with normal semen analysis tests in private laboratories. After analysis of semen quality, DNA was extracted from each sample by DNA MAX kit, then Samples were evaluated for these two pathogens by PCR. Results were statistically analyzed.

Results: Neisseria gonorrhoeae and U. urealyticum was detected by around 2% and 26% in samples of infertile men, respectively. The rate of infection were 0% and 8% in control group, respectively. Our data revealed that there was a significant association between male infertility and U. urealyticum infection (p=0.031). However, there was not a significant relationship between male infertility and N. gonorrhoeae infection (p=1). There was also no significant relationship between age groups (p=0.38).

Conclusions: Regarding the high frequency of N. gonorrhoeae and Ureaplasma urealyticum infection in infertile men compared with the control samples, screening test seems to be valuable to detect U. urealyticum and Neisseria gonorrhoeae infection and prevent infertility in men.

Keywords: Neisseria gonorrhoeae, Ureaplasma urealyticum, Male infertility, PCR

Full-Text [PDF 918 kb] (3616 Downloads)

Type of Study: Original Research Article | Subject: Medical Bacteriology
Received: 2015/11/14 | Accepted: 2016/01/20 | ePublished: 2016/10/16

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