year 19, Issue 4 (July - August 2025)
Iran J Med Microbiol 2025, 19(4): 8-8 |
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Mohseni M, Ahady M T, Fardin M. Antibiotic Resistance Profiling and mecA Gene Detection in Diabetic Foot Infections: A Study from Ardabil City, Iran. Iran J Med Microbiol 2025; 19 (4) :8-8
URL: http://ijmm.ir/article-1-2562-en.html
URL: http://ijmm.ir/article-1-2562-en.html
1- Department of Biology, Ardabil Branch, Islamic Azad University, Ardabil, Iran
2- Department of Biology, Ardabil Branch, Islamic Azad University, Ardabil, Iran. ,mot_ahadi@iauardabil.ac.ir
3- Department of Biology, Ardabil Branch, Islamic Azad University, Ardabil, Iran.
2- Department of Biology, Ardabil Branch, Islamic Azad University, Ardabil, Iran. ,
3- Department of Biology, Ardabil Branch, Islamic Azad University, Ardabil, Iran.
Abstract: (410 Views)
Background & Objective: Diabetic foot infections (DFIs) are a common complication for individuals with diabetes. The aim of this study is to monitor the presence of the mecA gene in diabetic foot infections in Ardabil city, northwest Iran.
Methods: A total of eighty samples were collected from Imam Khomeini Hospital in Ardabil, Iran, between March and February 2023. Bacterial isolates were identified using conventional microbiological techniques, and their antibiotic susceptibility was tested. The presence of the mecA gene was determined by PCR assay.
Results& Conclusion: A total of 119 bacterial strains were isolated from 80 diabetic foot ulcer samples. The most common were Staphylococcus aureus (34 isolates) and coagulase-negative Staphylococcus (21). E. coli was found in 18 isolates, with Citrobacter and Enterobacter each in 5, and Enterococcus in 18. Pseudomonas aeruginosa and Acinetobacter spp. were also detected. All Gram-positive bacteria were susceptible to linezolid, and Enterobacteriaceae to imipenem. PCR revealed 12 MRSA strains, all carrying the mecA gene. The high MRSA prevalence indicates increased antibiotic use and emerging resistance trends.
Type of Study: Brief Original Article |
Subject:
Medical Bacteriology
Received: 2025/06/26 | Accepted: 2025/09/9 | ePublished: 2025/10/10
Received: 2025/06/26 | Accepted: 2025/09/9 | ePublished: 2025/10/10
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