year 16, Issue 5 (September - October 2022)
Iran J Med Microbiol 2022, 16(5): 447-456 |
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Lotfi H, Khalilzadeh T, Damchi M, Hassan M. Biocides Susceptibility of Clinically Isolated Escherichia coli in Presence and Without Organic Material. Iran J Med Microbiol 2022; 16 (5) :447-456
URL: http://ijmm.ir/article-1-1614-en.html
URL: http://ijmm.ir/article-1-1614-en.html
1- Zanjan pharmaceutical biotechnology research center, Zanjan University of Medical Sciences, Zanjan, Iran
2- Department of Medicine, Faculty of Medicine, Laval University, Quebec, Canada
3- Zanjan pharmaceutical biotechnology research center, Zanjan University of Medical Sciences, Zanjan, Iran , maryambee2006@yahoo.com
2- Department of Medicine, Faculty of Medicine, Laval University, Quebec, Canada
3- Zanjan pharmaceutical biotechnology research center, Zanjan University of Medical Sciences, Zanjan, Iran , maryambee2006@yahoo.com
Abstract: (1482 Views)
Background and Aim: Hospital-acquired infections are considered a major health concern worldwide because of the increasing morbidity and mortality rate. Hence, selecting the most efficient disinfectants in a clinic is crucial. This study evaluated the antibacterial efficacy of seven mostly used disinfectants against clinically isolated Escherichia coli.
Materials and Methods: For this purpose, minimum inhibitory concentrations (MIC) and minimum bactericidal concentrations (MBC) of Aniosyme DD1 0.5%, Steranios 2%, Aniospray 29 and Surfanios 0.5% at Hazrat Valiasr hospital and PROSEPT® Floor 0.75%, PROSEPT® Instru 0.05% and PROSEPT® Med used at Ayatollah Mousavi hospital were determined both in the presence and absence of bovine serum albumin (BSA) using microbroth dilution assay.
Results: The results indicate that PROSEPT® Med had the lowest MIC and MBC values, followed by Aniospray 29 and PROSEPT® Instro, and the presence of BSA reduced antibacterial activities of disinfectants.
Conclusion: The disinfectants applied at Ayatollah Mousavi hospital generally had higher antibacterial activities. Due to the importance of nosocomial pathogens at healthcare centers, selecting the most potent, fast-acting, and efficient disinfectants to prevent hospital-acquired infections is essential.
Keywords: Disinfectants, Escherichia coli, Hospital-acquired infections, Minimum bactericidal concentrations, Minimum inhibitory concentrations
Type of Study: Original Research Article |
Subject:
Antibiotic Resistance
Received: 2022/01/5 | Accepted: 2022/05/17 | ePublished: 2022/08/8
Received: 2022/01/5 | Accepted: 2022/05/17 | ePublished: 2022/08/8
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