year 2, Issue 1 (Spring 2008)                   Iran J Med Microbiol 2008, 2(1): 45-51 | Back to browse issues page

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Tahmourespour A, Kasra-Kermanshahi R, Salehi R, Nabi-nejad A. The effect of lactobacillus fermentumATCC9338 as a probiotic on the adhesion of oral streptococci in vitro. Iran J Med Microbiol. 2008; 2 (1) :45-51
1- Islamic Azad University, Khorasgan Branch, Khorasgan, Isfahan
2- Department of Biological Science, Alzahra University, Tehran
3- Department of Biological Science, Isfahan University, Isfahan
4- Agricultural Research Center, Ministry of Jihad-Keshavarzi
Abstract:   (15042 Views)
Background and Objectives: Oral Streptococci especially Streptococcus mutans are the major cause of dental caries & periodontal diseases. Going along with the increasing antibiotic resistance of bacteria, new methods for decreasing of oral cavity pathogens must be investigated. The aim of this study was to determine the effect of lactobacillus fermentum ATCC9338 as a probiotic strain on the adhesion of oral streptococci to the surfaces.
Material and Methods: S. mutans ATCC35668 with oral streptococci isolated from dental plaque & caries (40 isolates) were studied. The ability of biofilm formation was investigated using the colorimetric method. An isolates showing the strongest activity in forming biofilm were selected. Then the effect of probiotic strain on the adhesion of the selected isolate to the polystyrene microtiter plate was determined simultaneously and 30 minutes before streptococci entrance to the system.
Results: this study showed that in the presence of probiotic strain, the streptococcal adhesion were reduced, and this reduction was significantly stronger if the probiotic strain was inoculated to the system before the oral bacteria. Adhesion reduction is likely due to bacterial interactions and colonization of adhesion sites with probiotic strain before the presence of streptococci.
Conclusion: Adhesion reduction can be an effective way on decreasing cariogenic potential of oral streptococci.
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Type of Study: Original | Subject: Antimicrobial Substances
Received: 2013/11/14 | Accepted: 2013/11/14

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