Iranian Journal of Medical Microbiology

en The Association Between Oral Candidiasis and ABO Blood Type in Infants in Kirkuk City, Iraq قارچ شناسی پزشکی Medical Mycology مقاله پژوهشی Original Research Article   Introduction and Objective: Candidiasis is the most prevalent mouth fungal infection. It is unclear whether variations in human blood types contribute to the onset of this illness. We aimed to identify the association between blood type antigens (ABO) and oral candidiasis in infants. Material and methods: The specimens were taken from 110 infants with oral candidiasis symptoms, ages between 1 and 18 months, primarily from the Children's Hospital in Kirkuk City and a few outlying clinics. . Direct hemagglutination technique was conducted using monoclonal antibodies against human A, B, and Rh D antigens of the blood types. Macroscopic and microscopic evaluations were also performed. Chromogenic Agar Candida (CAC) was used to selectively develop the isolates with characteristic of Candida spp. Results: The results showed significant difference between 72 positive infants (65%) and 38 infants without oral candidiasis (35%) (P<0.05). Most infected infants were males (67%), age groups 7-12 months (60%) with O+ (46%), A+ (26%) and Rh+ (92%) blood groups with significant differences (P<0.05). The Candida (C.) albicans scored the highest infection (85%) followed by the C. glabrata (8%), C. krusei (6%), and C. tropicalis (1%) with significant differences (P<0.05). Conclusions: The prevalence of oral candidiasis in infants was related to the impaired immune status. Most infections with these diseases were in males age ranged 7-12 months with A+, O+, and Rh+ blood groups. C. albicans recorded the highest prevalence for the oral infants’ cases compared to the other studied candida types because of the highest pathogenicity. Oral candidiasis, C. albicans, Oral infection, Blood group (ABO) 301 307 http://ijmm.ir/browse.php?a_code=A-10-2627-1&slc_lang=en&sid=1 Iman Tajer Abdullah imantajer@uokirkuk.edu.iq 100319475328460030753 100319475328460030753 No Department of Biology, College of Science, University of Kirkuk, Kirkuk, Iraq Asoda M. Noori asuda.nori@gmail.com 100319475328460030754 0009-0001-9284-3608 Yes Department of Biology, College of Science, Garmian University, Sulaymaniyah, Iraq Bari Lateef Mohammed dr.pary.mycology@uokirkuk.edu.iq 100319475328460030755 100319475328460030755 No Department of Biology, College of Science, University of Kirkuk, Kirkuk, Iraq Shakhawan Beebany sh.beebany@uokirkuk.edu.iq 100319475328460030756 100319475328460030756 No Department of Chemistry, College of Science, University of Kirkuk, Kirkuk, Iraq