Iranian Journal of Medical Microbiology

en شیوع گونه های اسینتوباکتر جدا شده از نمونه های بالینی مراجعه کننده به بیمارستان الکفیل، عراق و الگوهای حساسیت آنتی بیوتیکی آنها از سال 2017-2021 Prevalence of Acinetobacter Species Isolated from Clinical Samples Referred to Al-Kafeel Hospital, Iraq and Their Antibiotic Susceptibility Patterns from 2017-2021 باکتری شناسی پزشکی Medical Bacteriology مقاله پژوهشی Original Research Article Background and Objective: Acinetobacter has been considered an important nosocomial pathogen since 1970. This study aims to investigate the prevalence of Acinetobacter infection during 2017-2021, study the antibiogram of these bacteria, and study the impact of gender on infection. Materials and Methods: This is a retrospective study in which data of the clinical samples received in Al-Kafeel Hospital, Kerbala, Iraq, between April 2017 and February 2021 were searched for Acinetobacter infection and their antibiotic susceptibility testing. Results: The prevalence of Acinetobacter infection was 9.2% of cases. Male to Female ratio was 3:1, and there was a significant difference in Acinetobacter infection regarding gender. There were high resistance rates to major antibiotic classes. Maximum resistance was recorded for Amoxicillin (100%), followed by 3rd generation cephalosporins, including Cefotaxime (92.3%), Ceftriaxone (91.6%), Ceftazidime (91.3%), Cefixime (80%); in addition to growing resistance to carbapenems, Imipenem (42.8%) and Meropenem (62.2%). The lowest resistance rates were found to colistin sulfate (10%). There 80.7% of the isolates were multidrug-resistant MDR. Conclusion: Acinetobacter spp., is considered as fast emerging opportunistic agents with evolving drug resistance. Rationale use of antibiotics is important and necessary to prevent microbial resistance. Gender is considered a risk factor for Acinetobacter infection. <div><div></div></div> Background and Objective: Acinetobacter has been considered an important nosocomial pathogen since 1970. This study aims to investigate the prevalence of Acinetobacter infection during 2017-2021, study the antibiogram of these bacteria, and study the impact of gender on infection. Materials and Methods: This is a retrospective study in which data of the clinical samples received in Al-Kafeel Hospital, Kerbala, Iraq, between April 2017 and February 2021 were searched for Acinetobacter infection and their antibiotic susceptibility testing. Results: The prevalence of Acinetobacter infection was 9.2% of cases. Male to Female ratio was 3:1, and there was a significant difference in Acinetobacter infection regarding gender. There were high resistance rates to major antibiotic classes. Maximum resistance was recorded for Amoxicillin (100%), followed by 3rd generation cephalosporins, including Cefotaxime (92.3%), Ceftriaxone (91.6%), Ceftazidime (91.3%), Cefixime (80%); in addition to growing resistance to carbapenems, Imipenem (42.8%) and Meropenem (62.2%). The lowest resistance rates were found to colistin sulfate (10%). There 80.7% of the isolates were multidrug-resistant MDR. Conclusion: Acinetobacter spp., is considered as fast emerging opportunistic agents with evolving drug resistance. Rationale use of antibiotics is important and necessary to prevent microbial resistance. Gender is considered a risk factor for Acinetobacter infection. <div><div></div></div> Acinetobacter spp., Antibiotic Susceptibility test, Sex differences, MDR, Iraq 76 82 http://ijmm.ir/browse.php?a_code=A-10-1640-1&slc_lang=en&sid=1 Suhad Hadi Mohammed سوهاد هادی محمد shm.med.school@gmail.com 100319475328460018979 100319475328460018979 Yes Department of Clinical Laboratories, College of Applied Medical Sciences, Kerbala University, Kerbala, Iraq گروه آزمایشگاه های بالینی، دانشکده علوم پزشکی کاربردی، دانشگاه کربلا، کربلا، عراق Mohanad Mohsen Ahmed محند محسن احمد dr.mohma.med.school@gmail.com 100319475328460018980 100319475328460018980 No Department of Microbiology, College of Medicine, Kerbala University, Kerbala, Iraq گروه میکروبیولوژی، دانشکده پزشکی، دانشگاه کربلا، کربلا، عراق Narjes Abd Alameer Abd Alredaa نرجس عبدالعمار عبدالردا m16171030@s.uokerbala.edu.iq 100319475328460018981 100319475328460018981 No Department of Clinical Laboratories, College of Applied Medical Sciences, Kerbala University, Kerbala, Iraq گروه آزمایشگاه های بالینی، دانشکده علوم پزشکی کاربردی، دانشگاه کربلا، کربلا، عراق Huda Haider Abd Alabbas هدی حیدر عبد العباس e16161247@s.uokerbala.edu.iq 100319475328460018982 100319475328460018982 No Department of Clinical Laboratories, College of Applied Medical Sciences, Kerbala University, Kerbala, Iraq گروه آزمایشگاه های بالینی، دانشکده علوم پزشکی کاربردی، دانشگاه کربلا، کربلا، عراق Zainab Dheyaa Mohammad Ali زینب محمدعلی m16171015@s.uokerbala.edu.iq 100319475328460018983 100319475328460018983 No Department of Clinical Laboratories, College of Applied Medical Sciences, Kerbala University, Kerbala, Iraq گروه آزمایشگاه های بالینی، دانشکده علوم پزشکی کاربردی، دانشگاه کربلا، کربلا، عراق Zahraa Zuher Abed Al-Wahab زهرا زحیر عابد الوهاب e16161267@s.uokerbala.edu.iq 100319475328460018984 100319475328460018984 No Department of Clinical Laboratories, College of Applied Medical Sciences, Kerbala University, Kerbala, Iraq گروه آزمایشگاه های بالینی، دانشکده علوم پزشکی کاربردی، دانشگاه کربلا، کربلا، عراق Zainab Ali Mohsin زینب علی محسن e16161275@s.uokerbala.edu.iq 100319475328460018985 100319475328460018985 No Department of Clinical Laboratories, College of Applied Medical Sciences, Kerbala University, Kerbala, Iraq گروه آزمایشگاه های بالینی، دانشکده علوم پزشکی کاربردی، دانشگاه کربلا، کربلا، عراق Zahraa Jalil Jasim Mohammed زهرا جلیل حاسم محمد e16161265@s.uokerbala.edu.iq 100319475328460018986 100319475328460018986 No Department of Clinical Laboratories, College of Applied Medical Sciences, Kerbala University, Kerbala, Iraq گروه آزمایشگاه های بالینی، دانشکده علوم پزشکی کاربردی، دانشگاه کربلا، کربلا، عراق Zahraa Abd Al Hamza Mohammed زهرا عبدالحمزه محمد e16161268@s.uokerbala.edu.iq 100319475328460018987 100319475328460018987 No Department of Clinical Laboratories, College of Applied Medical Sciences, Kerbala University, Kerbala, Iraq گروه آزمایشگاه های بالینی، دانشکده علوم پزشکی کاربردی، دانشگاه کربلا، کربلا، عراق Noor Yahya Abid Zaid نور یحیی عابید زیاد nooralshimary068@gmail.com 100319475328460018988 100319475328460018988 No Department of Clinical Laboratories, College of Applied Medical Sciences, Kerbala University, Kerbala, Iraq گروه آزمایشگاه های بالینی، دانشکده علوم پزشکی کاربردی، دانشگاه کربلا، کربلا، عراق