@ARTICLE{Monavari, author = {Tavakoli, Ahmad and Karbalaie Niya, Mohammad Hadi and Keshavarz, Mohsen and Safarnezhad Tameshke, Fahimeh and Monavari, Seyed Hamidreza and }, title = {Middle East Respiratory Syndrome Coronavirus (MERS-CoV)}, volume = {11}, number = {1}, abstract ={The Middle East respiratory syndrome coronavirus (MERS-CoV) as a causative agent of severe lower respiratory tract infection in humans, considered as a global threat, especially against to Persian Gulf countries. Since its discovery in 2012, MERS-CoV has spread 27 countries affecting about 1800 people and caused more than 600 deaths in worldwide. In comparison to SARS (severe acute respiratory syndrome), MERS-CoV appears to have a higher mortality rate (40% versus 10%) and is particularly more severe in patients with underlying medical conditions. Until now, the most MERS-CoV cases (more than 85 percent) have had a history of travel or residence in the Middle East countries. A possible intermediate host for MERS-CoV is camel. Clinical manifestations of MERS range from mild or asymptomatic disease to acute respiratory syndrome and multi-organ failure resulting in death, mostly in individuals with preexisting medical co-morbidities. There is no specific antiviral treatment for MERS and infection prevention and control practices are necessary to prevent spread of MERS-CoV in health care facilities. In present study, we have briefly outlined the recent information about the epidemiology, clinical features, diagnosis, treatment and prevention of MERS-CoV. }, URL = {http://ijmm.ir/article-1-582-en.html}, eprint = {http://ijmm.ir/article-1-582-en.pdf}, journal = {Iranian Journal of Medical Microbiology}, doi = {}, year = {2017} }