@ARTICLE{Roghanian, author = {Karimian, Reyhaneh and Roghanian, Rasoul and Etemadifar, Zahra and }, title = {Study of accosiation between male infertility and Neisseria gonorrhoeae and Ureaplasma urealyticum infection}, volume = {10}, number = {3}, abstract ={Background and Aim: Neisseria gonorrhoeae and Ureaplasma urealyticum are the main cause of genital infections and infertility in both genders. However, there are few studies regarding N. gonorrhoeae in semen samples of infertile men. Therefore, the aim of this study was the prevalence of N. gonorrhoeae and U. urealyticum infection in infertile men. Materials and Methods: 100 samples were collected from two groups. The first group was 50 samples from men with abnormal semen analysis tests In Isfahan Fertility and Infertility Center and the second was 50 samples from men with normal semen analysis tests in private laboratories. After analysis of semen quality, DNA was extracted from each sample by DNA MAX kit, then Samples were evaluated for these two pathogens by PCR. Results were statistically analyzed. Results: Neisseria gonorrhoeae and U. urealyticum was detected by around 2% and 26% in samples of infertile men, respectively. The rate of infection were 0% and 8% in control group, respectively. Our data revealed that there was a significant association between male infertility and U. urealyticum infection (p=0.031). However, there was not a significant relationship between male infertility and N. gonorrhoeae infection (p=1). There was also no significant relationship between age groups (p=0.38). Conclusions: Regarding the high frequency of N. gonorrhoeae and Ureaplasma urealyticum infection in infertile men compared with the control samples, screening test seems to be valuable to detect U. urealyticum and Neisseria gonorrhoeae infection and prevent infertility in men. }, URL = {http://ijmm.ir/article-1-505-en.html}, eprint = {http://ijmm.ir/article-1-505-en.pdf}, journal = {Iranian Journal of Medical Microbiology}, doi = {}, year = {2016} }