TY - JOUR JF - Iran-J-Med-Microbiol JO - Iran J Med Microbiol VL - 17 IS - 2 PY - 2023 Y1 - 2023/4/01 TI - The Effect of SARS-COV-2 Infection on the Hematological Markers TT - تأثیر عفونت SARS-COV-2 بر مارکرهای خونی N2 - Background and Aim: The novel coronavirus 2019 can lead to a vast range of respiratory complications, from mild to severe, driving to acute respiratory distress syndrome (ARDS). Common symptoms of COVID-19 include fever, fatigue, and dry cough, which can lead to complications, such as gastrointestinal disorders, and liver, cardiac, and renal dysfunctions. Alteration in the hematological markers is one of the COVID-19 diseases evaluated by our study. Materials and Methods: In this study, hematological markers, including the levels of ESR, BS, Hb, HCT, MCV, MCH, MCHC, platelet, WBC, RBC, neutrophil, and lymphocyte, have been assessed and compared in both case and control groups. Furthermore, we assessed the associations between hematological parameters, clinical manifestations, and underlying medical conditions. Results: Our data showed that RBC, HCT, and ESR were significantly associated with the novel coronavirus 2019 infection according to the disease progression. ESR (P= 0.022), Hb (P= 0.032), and BS (P= 0.01) levels in male people infected by SARS-CoV-2 proved to have a significant relationship with the control group. Moreover, BS, Hb, HCT, ESR, and neutrophil showed significant variations in diabetic individuals suffering from SARS-CoV-2 infection. Conclusion: The dropping of the hematological markers in COVID-19 is linked with a noticeably increased mortality rate, while high neutrophil and BS levels are related to aggravation of the disease. Monitoring the hematological markers can contribute significantly to selecting the proper treatment and hamper of disease worsening. SP - 202 EP - 210 AU - Fatahi, Seyed Majid AU - Khanizadeh, Sayyad AU - Safarzadeh, Ali AU - Alamdary, Ashkan AU - Razavi Nikoo, Hadi AU - Mohammadi, Rasool AU - Ghalandarian, Annahita AU - Ajorloo, Mehdi AD - Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran KW - COVID-19 KW - SARS-CoV-2 KW - Hematological KW - Marker UR - http://ijmm.ir/article-1-1803-en.html DO - 10.30699/ijmm.17.2.202 ER -