AU - Kaur, Puneet AU - Sachan, Rohan Samir Kumar AU - Karnwal, Arun AU - Devgon, Inderpal TI - A Review on Clinical Manifestation and Treatment Regimens of UTI in Diabetic Patients PT - JOURNAL ARTICLE TA - Iran-J-Med-Microbiol JN - Iran-J-Med-Microbiol VO - 16 VI - 2 IP - 2 4099 - http://ijmm.ir/article-1-1408-en.html 4100 - http://ijmm.ir/article-1-1408-en.pdf SO - Iran-J-Med-Microbiol 2 ABĀ  - The pervasiveness of urinary tract infections (UTIs) with their clinical manifestations in patients with diabetes mellitus has escalated amidst the past decade or so, as myriad predisposing factors contribute to its occurrence. Although the causative agent of UTI is Escherichia coli, the etiopathogenesis can be traced back to glycosuria in the renal parenchymal region. This has precipitated pyelonephritis and renal complications, including cytopathic and altered metabolism. Furthermore, impaired immunity with scarce IL-6, 8 in urine, urinary retention, and dysfunctional voiding raise susceptibility towards uropathogens, mainly E. coli. Treatment for UTI with diabetes is based on symptoms and severity, urologic abnormalities, renal function, bladder infections, and metabolic alteration. The treatment process or regimens for patients with type 2 diabetes with asymptomatic bacteriuria are very low or negligible. Adequate management with antibiotic regimens in symptomatic patients after critical diagnosis is crucial for prophylaxis and effective treatment. CP - IRAN IN - Department of Microbiology, Lovely Professional University, Phagwara, Punjab, India LG - eng PB - Iran-J-Med-Microbiol PG - 98 PT - Review Article YR - 2022