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Iran J Med Microbiol 2007, 1(1): 55-60 |
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Mirsalehian A, Razavi S M, Ziaei H, Bamdad K, Mirafshar S M, Bazarjani F. Titration of specific antibodies to Mycoplasma pneuomoniae, Chlamydia pneumoniae andLegionella pneumophila among Iranian pilgrims' sera during Hajj seasonin 2004. Iran J Med Microbiol 2007; 1 (1) :55-60
URL: http://ijmm.ir/article-1-74-en.html
URL: http://ijmm.ir/article-1-74-en.html
Akbar Mirsalehian 
1, Seyed Mansour Razavi1 , Hossein Ziaei1 , Kobra Bamdad2 , Seyed mohammad Mirafshar1 , Farzaneh Bazarjani1
1, Seyed Mansour Razavi1 , Hossein Ziaei1 , Kobra Bamdad2 , Seyed mohammad Mirafshar1 , Farzaneh Bazarjani1
1- Department of Microbiology, School of Medicine, Tehran University of Medical Sciences
2- Department of Ophthalmology, School of Medicine, Shahid Beheshti University of Medical Sciences
2- Department of Ophthalmology, School of Medicine, Shahid Beheshti University of Medical Sciences
Abstract: (15005 Views)
Background and objectives: Respiratory tract infection is the most common diseases among Iranian
pilgrims during Hajj season. To understand the possibility of bacterial involvement in such infections, we
screened the pilgrims’ sera to determine the titer of antibodies against Mycoplasma pneuomoniae (MP),
Chlamydia pneumoniae (CP) and Legionella pneumophila (LP).
Material and Method: Serum samples from 128 pilgrims were collected, before the trip and one month after returning home. Antibodies to MP, CP, LP were assayed using Immunoflourecent and ELISA methods.
Results: IgM antibody titre to CP did not elevated, but IgG antibody titer was increased in 34.58% (n=48) and 15.82% (n=22) of cases, indicating of recent infection. The specific antibodies to MP and LP were not increased.
Conclusion: In pilgrims infected with an atypical respiratory pathogen, C. pneumoniae should be considered as an important causative. The true prevalence of thispathogen should be investigated since it relies on the sensitivity and specificity of currently available diagnostic methods.
Material and Method: Serum samples from 128 pilgrims were collected, before the trip and one month after returning home. Antibodies to MP, CP, LP were assayed using Immunoflourecent and ELISA methods.
Results: IgM antibody titre to CP did not elevated, but IgG antibody titer was increased in 34.58% (n=48) and 15.82% (n=22) of cases, indicating of recent infection. The specific antibodies to MP and LP were not increased.
Conclusion: In pilgrims infected with an atypical respiratory pathogen, C. pneumoniae should be considered as an important causative. The true prevalence of thispathogen should be investigated since it relies on the sensitivity and specificity of currently available diagnostic methods.
Keywords: Mycoplasm pneuomoniae, Chlamydia pneumoniaeandLegionella pneumophilaantibodies, pilgrim, respiratory infections, antibody titration
Type of Study: Original Research Article |
Subject:
Medical Bacteriology
Received: 2013/11/10 | Accepted: 2013/11/10 | ePublished: 2013/11/10
Received: 2013/11/10 | Accepted: 2013/11/10 | ePublished: 2013/11/10
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