Sample Size in Animal Studies (The number of laboratory animals in a Research study)

Alimohamadi, Yousef; Sepandi, Mojtaba

doi:10.30699/ijmm.16.2.173

year 16, Issue 2 (March - April 2022) Iran J Med Microbiol 2022, 16(2): 173-176 | Back to browse issues page

‎ 10.30699/ijmm.16.2.173

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Alimohamadi Y, Sepandi M. Sample Size in Animal Studies (The number of laboratory animals in a Research study). Iran J Med Microbiol 2022; 16 (2) :173-176
URL: http://ijmm.ir/article-1-1566-en.html

Sample Size in Animal Studies (The number of laboratory animals in a Research study)

Yousef Alimohamadi¹

, Mojtaba Sepandi

1- Health Research Center, Life Style Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran
2- Exercise Physiology Research Center, Life Style Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran , msepandi@gmail.com

Abstract: (1769 Views)

Before interventional clinical studies in humans, researchers usually perform preclinical studies in vitro or in vivo to evaluate the initial efficacy, toxicity, and pharmacokinetics of interventions. Sample size determination in animal studies is necessary both in terms of correct and scientific inference and in terms of ethics. Therefore, the purpose of this paper is a brief description of how to determine the sample size in a study on laboratory animals.

Keywords: Laboratory animals, Sample size, Study power, Laboratory studies

Full-Text [PDF 542 kb] (730 Downloads) | | Full-Text (HTML) (1629 Views)

Type of Study: Letter to the Editor | Subject: Deep learning
Received: 2021/11/27 | Accepted: 2022/01/14 | ePublished: 2022/02/10

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