The Evaluation Anti-HBsAb Titer Among University Students in Shiraz, 2019

Hashemi, Seyed Mohammad Ali; Hashemzadeh, Fatemeh; Bahrampour, Helen; Nekoei, Fatemeh; Joharinia, Negar; Sarvari, Jamal

doi:10.30699/ijmm.14.4.297

year 14, Issue 4 (July - August 2020) Iran J Med Microbiol 2020, 14(4): 297-306 | Back to browse issues page

‎ 10.30699/ijmm.14.4.297

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Hashemi S M A, Hashemzadeh F, Bahrampour H, Nekoei F, Joharinia N, Sarvari J. The Evaluation Anti-HBsAb Titer Among University Students in Shiraz, 2019. Iran J Med Microbiol 2020; 14 (4) :297-306
URL: http://ijmm.ir/article-1-1106-en.html

The Evaluation Anti-HBsAb Titer Among University Students in Shiraz, 2019

Seyed Mohammad Ali Hashemi¹

, Fatemeh Hashemzadeh¹

, Helen Bahrampour¹

, Fatemeh Nekoei¹

, Negar Joharinia¹

, Jamal Sarvari

1- Department of Bacteriology & Virology, Shiraz University of Medical Sciences, Shiraz, Iran
2- Gastroenterohepatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran , sarvarij@sums.ac.ir

Abstract: (5341 Views)

Background: Regarding the availability of an effective vaccine against hepatitis B virus, global vaccination is the best cost-effective strategy to prevent HBV infection. However, some people may not respond to the vaccine or the titer of antibody decreases by time. Therefore, the present study aimed to determine the frequency of anti-HBs antibody (anti-HBsAb), among university students in Fars province, southern Iran.

Methods: In this cross-sectional study, 825 medical students were enrolled. Blood samples were taken from the subjects, and the serum separated and stored at – 20 ºC until use. Next, HBs Ab titer was measured by ELISA method.

Results: Out of 825 students 54% was male and 46% were female. The mean age of the students was 19.5±1.9. The titer of anti-HBsAb in 529 (64%) of subjects was lower than 10 mIU/mL. Significant relationship was observed between age and the titer of anti-HBsAb (P=0.001), although no significant relationship was observed between gender (P=0.19), history of blood transfusion (P=0.58) and the titer of anti-HBsAb.

Conclusion: Finding of this study showed that the titer of anti-HBsAb in more than half of students was lower than 10 mIU/mL and by time the anti-HBsAb titer decreased, indicating the necessity of measurement of anti-HBsAb titer in medical students.

Keywords: Hepatitis B virus, Antibody titer, Student, Shiraz

Full-Text [PDF 779 kb] (1519 Downloads) | | Full-Text (HTML) (1254 Views)

Type of Study: Original Research Article | Subject: Medical Virology
Received: 2020/04/12 | Accepted: 2020/07/18 | ePublished: 2020/08/20

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