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:: Volume 11, Number 1 (2017) ::
Back to browse issues page Iran J Med Microbiol 2017, 11(1): 1-8
Middle East Respiratory Syndrome Coronavirus (MERS-CoV)
Ahmad Tavakoli1, Mohammad Hadi Karbalaie Niya1, Mohsen Keshavarz1, Fahimeh Safarnezhad Tameshke2, Seyed Hamidreza Monavari *3
1- Department of Virology, Faculty of medicine, Iran University of Medical Sciences, Tehran, Iran
2- Gastrointestinal & Liver Disease Research Center (GILDRC), Iran University of Medical Sciences, Tehran, Iran
3- Department of Virology, Faculty of medicine, Iran University of Medical Sciences, Tehran, Iran , hrmonavari@yahoo.com
Abstract:   (129 Views)

The Middle East respiratory syndrome coronavirus (MERS-CoV) as a causative agent of severe lower respiratory tract infection in humans, considered as a global threat, especially against to Persian Gulf countries. Since its discovery in 2012, MERS-CoV has spread 27 countries affecting about 1800 people and caused more than 600 deaths in worldwide. In comparison to SARS (severe acute respiratory syndrome), MERS-CoV appears to have a higher mortality rate (40% versus 10%) and is particularly more severe in patients with underlying medical conditions. Until now, the most MERS-CoV cases (more than 85 percent) have had a history of travel or residence in the Middle East countries. A possible intermediate host for MERS-CoV is camel. Clinical manifestations of MERS range from mild or asymptomatic disease to acute respiratory syndrome and multi-organ failure resulting in death, mostly in individuals with preexisting medical co-morbidities. There is no specific antiviral treatment for MERS and infection prevention and control practices are necessary to prevent spread of MERS-CoV in health care facilities. In present study, we have briefly outlined the recent information about the epidemiology, clinical features, diagnosis, treatment and prevention of MERS-CoV.

Keywords: Middle East respiratory syndrome, MERS-CoV, Acute respiratory illness, SARS
Full-Text [PDF 649 kb]   (88 Downloads)    
Type of Study: Review | Subject: Medical Virology
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Tavakoli A, Karbalaie Niya M H, Keshavarz M, Safarnezhad Tameshke F, Monavari S H. Middle East Respiratory Syndrome Coronavirus (MERS-CoV). Iran J Med Microbiol. 2017; 11 (1) :1-8
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Back to browse issues page Volume 11, Number 1 (2017)
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