year 2, Issue 3 And 4 (3-2009)
Iran J Med Microbiol 2009, 2(3 And 4): 79-85 |
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Sharifi M, Sareshtedari M, Hassani F, Reissi B, AlipourHeidary M. Prevalence of and some risk factors for methicillin-resistant Staphylococcus aureusnasal colonization in hospitalized children. Iran J Med Microbiol 2009; 2 (3 and 4) :79-85
URL: http://ijmm.ir/article-1-133-en.html
URL: http://ijmm.ir/article-1-133-en.html
Masoud Sharifi 
1, Mahshid Sareshtedari2 , Farnaz Hassani3 , Bahareh Reissi3 , Mahmood AlipourHeidary4
1, Mahshid Sareshtedari2 , Farnaz Hassani3 , Bahareh Reissi3 , Mahmood AlipourHeidary4
1- Department of Microbiology, School of Medicine, Qazvin university of Medical Sciences , dr_m_sharifi2002@yahoo.com
2- Department of Pediatrics, School of Medicine, Qazvin university of Medical Sciences
3- General Physician
4- Department of CommunityMedicine, School of Medicine, Qazvin university of Medical Sciences
2- Department of Pediatrics, School of Medicine, Qazvin university of Medical Sciences
3- General Physician
4- Department of CommunityMedicine, School of Medicine, Qazvin university of Medical Sciences
Abstract: (14636 Views)
Background and objectives: The adaptive power of Staphylococcus aureus(S.aureus) to antibiotics leaded,
in the early 1960s, to the emergence of methicillin-resistant S. aureus (MRSA). The early MRSA clones
were hospital-associated (HA-MRSA). However, from the late 1990s, community-associated MRSA (CAMRSA) clones emerged worldwide. Patient’s study on the admission and the discharge provides an
important information about the position of CA-MRSA , the rate of HA-MRSA colonization ,and risk factors
for colonization. This information could be used for prevention of organism transmission, control of hospital
environment, and prevention of hospital organisms spread into community. The aim of this study was to
determine the prevalence of and some risk factors of methicillin- resistant S.aureus nasal colonization in
hospitalized children.
Materials and Methods: Nasal swab specimens were collected on the admission and the discharge of patients admitted in the Qods educational and health pediatrics center of Qazvin. After isolation and identification the strains, the methicillin resistance was determined by Clinical and laboratory standards institute(CLSI) oxacillin screening plate method. Other information were collected by questionnaire. The data were analyzed by Chi-square test.
Results: A total number of 200 patients (2 to 12 years old) were studied. The carrier state of methicillin sensitive S. aureus(MSSA), and MRSA strains were 6 (3%),and 1 (0.5%) respectively. From 193 remainder on discharging 14 (9%), and 3 (1.9%) patients were colonized with MSSA, and MRSA strains respectively. Ceftriaxone was administrated for all patients colonized with MRSA strains. There was no significant correlation between colonization with MRSA strains and studied variables.
Conclusion: Our findings confirm the presence of MRSA strain in children population in Qazvin city. The incidence of colonization with MSSA, and MRSA , in comparison of the carrier state with the same strains, were 2/4 , and 3.2 times. This rate is higher in the case of MRSA , which is correlated with administration of Ceftriaxon.
Materials and Methods: Nasal swab specimens were collected on the admission and the discharge of patients admitted in the Qods educational and health pediatrics center of Qazvin. After isolation and identification the strains, the methicillin resistance was determined by Clinical and laboratory standards institute(CLSI) oxacillin screening plate method. Other information were collected by questionnaire. The data were analyzed by Chi-square test.
Results: A total number of 200 patients (2 to 12 years old) were studied. The carrier state of methicillin sensitive S. aureus(MSSA), and MRSA strains were 6 (3%),and 1 (0.5%) respectively. From 193 remainder on discharging 14 (9%), and 3 (1.9%) patients were colonized with MSSA, and MRSA strains respectively. Ceftriaxone was administrated for all patients colonized with MRSA strains. There was no significant correlation between colonization with MRSA strains and studied variables.
Conclusion: Our findings confirm the presence of MRSA strain in children population in Qazvin city. The incidence of colonization with MSSA, and MRSA , in comparison of the carrier state with the same strains, were 2/4 , and 3.2 times. This rate is higher in the case of MRSA , which is correlated with administration of Ceftriaxon.
Type of Study: Original Research Article |
Subject:
Medical Bacteriology
Received: 2013/11/16 | Accepted: 2013/11/16 | ePublished: 2013/11/16
Received: 2013/11/16 | Accepted: 2013/11/16 | ePublished: 2013/11/16
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