[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: year 2, Issue 1 (Spring 2008) ::
Iran J Med Microbiol 2008, 2(1): 53-58 Back to browse issues page
The effect of Sub-Minimum Inhibitory Concentration (S-MIC) of ciprofloxacin & ampicillin on hemolysin activity of Escherichia coli
Seyed Asghar Havaei 1, Morteza Satari 2, Mojgan Oshaghi 2, Abdolrazagh Hashemi Shahraki 3
1- Department of Microbiology , Isfahan University of Medical Sciences , havaei @med.mui.ac.ir
2- Department of Microbiology, School of Medical Sciences, Tarbiat Modarres University, Tehran, Iran.
3- Department of Microbiology , Isfahan University of Medical Sciences
Abstract:   (10496 Views)
Background and objectives: Sub-minimum inhibitory concentration (S-MIC) can induce changes in morphology, virulence factors and biochemical properties ofbacterial pathogens. The goal of this study is to determine the Sub-MIC effect of ciprofloxacin and ampicillin on the haemotytic activity of E. coli.
Material and Methods:Two clinical isolates of E. coli with high heamolytic activity was selected. Changes in haemolytic activity of the isolates was assessed after exposing them to MIC and Sub-MIC of ciprofloxacin and ampicillin.
Results: Ciprofloxacin decreased haemolytic activity at 1/2, 1/4 and 1/8 Sub-Mic, whereas ampicillin showed no effect on haemolytic activity.
Conclusion:
We conclude that Sub-MIC concentrations of ciprofloxacin decreased the haemolytic activity of E. coli, wherease ampicillin had no such effect
Keywords: Mycobacterium bovis, Mycobacterium tuberculosiscomplex, oxyRpseudogene, PCR-RFLP, AluI
Full-Text [PDF 285 kb]   (2084 Downloads)    
Type of Study: Original | Subject: Medical Bacteriology
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA code


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Havaei S A, Satari M, Oshaghi M, Hashemi Shahraki A. The effect of Sub-Minimum Inhibitory Concentration (S-MIC) of ciprofloxacin & ampicillin on hemolysin activity of Escherichia coli . Iran J Med Microbiol. 2008; 2 (1) :53-58
URL: http://ijmm.ir/article-1-106-en.html


year 2, Issue 1 (Spring 2008) Back to browse issues page
مجله میکروب شناسی پزشکی ایران Iranian Journal of Medical Microbiology
Persian site map - English site map - Created in 0.05 seconds with 32 queries by YEKTAWEB 3862