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Iran J Med Microbiol 2017, 11(5): 83-89 Back to browse issues page
Relative Frequency of Influenza A/H1N1 Virus in Guilan Province, Iran
Vahideh Javid Khojasteh Dr 1, Ali Mojtahedi Dr2, Simin Hosseini 3, Farahnaz Joukar 4
1- Shahid Beheshti Nursing and Midwifery School of Rasht, Guilan University of Medical Sciences, Rasht, Iran , vahikj161@gmail.com
2- Rasht guilan university
3- Head of Laboratory of Vice-chancellor for health, Guilan University of Medical Sciences, Rasht, Iran
4- Department of Nursing, Gastroenterology and Liver Disease Research Center, Guilan University of Medical Sciences, Rasht, Iran
Abstract:   (1497 Views)

Background and Aims: Influenza A/H1N1, the cause of an acute respiratory illness, undergoes genetic changes every few years, resulting in a new subtype with new surface antigenic structure. The aim of this study was to investigate the prevalence of influenza A/H1N1 virus among specimens collected from patients with influenza symptoms who were admitted to educational and training hospitals in Guilan province, Iran.
Materials and Methods: This descriptive cross-sectional study was performed on upper respiratory tract discharges of patients with influenza symptoms in the counties of Guilan province, using Real-Time PCR technique in Gastrointestinal and Liver Diseases Research Center of Gilan University of Medical Sciences in 2015. The Fishers Exact Test or chi-square χ)2( was used for data analysis.
Results: From 108 patients with influenza symptoms, 58 (53/7%) were female. The age range of patients was between 1-78 years old. The results showed that only 4 (3/7%) patients were positive for A/H1N1virus (3 male and 1 female). This included a male who was admitted with pneumonia and expired later.  
Conclusions: Influenza virus A/H1N1 is a mutant virus, the genetic evolution in which is constantly occurring and new subtypes can, therefore, re-infect the community. It is thus imperative that vaccination is done to prevent against novel strains of influenza.

Keywords: Influenza virus subtype A/H1N1, Acute upper respiratory disease, Real time PCR, Prevalence.
Full-Text [PDF 701 kb]   (351 Downloads)    
Type of Study: Original | Subject: Medical Virology
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Javid Khojasteh V, Mojtahedi A, Hosseini S, Joukar F. Relative Frequency of Influenza A/H1N1 Virus in Guilan Province, Iran. Iran J Med Microbiol. 2017; 11 (5) :83-89
URL: http://ijmm.ir/article-1-554-en.html


year 11, Issue 5 (November - December 2017) Back to browse issues page
مجله میکروب شناسی پزشکی ایران Iranian Journal of Medical Microbiology
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